Metrogyl 400 Mg (Metronidazole)

Last Updated on 01/31/2026 ✔ Medically Reviewed by Dr. Arjun Srivastav

What Is Metrogyl 400 Mg?

Metrogyl 400 mg is an antibiotic medicine that contains Metronidazole 400 mg as its active ingredient. It is used to treat a variety of bacterial and parasitic infections in different parts of the body.

Metrogyl 400 works by killing harmful bacteria and protozoa and stopping their growth, helping the body recover from infection.

Metrogyl 400 is an antibiotic containing Metronidazole 400 mg.
It is commonly prescribed to treat bacterial and parasitic infections, especially those affecting the stomach, intestines, vagina, gums, skin, and joints.

Metrogyl 400 mg is an antibiotic, but with a wide range of infections to cure.

Parasitic infections like-

• Amoebic dysentery
• Giardiasis
• Trichomoniasis is a form of infection in the genitals

Anaerobic bacteria cause infections in areas like the stomach, lungs, brain, pelvic regions, and blood.

Other than this, it can also cure other infections.

• The gum region
• Stomach ulcers
• Leg ulcers
• Infection in the female uterus after childbirth

Inside each pill is the generic component Metronidazole, which has an anti-bacterial property.

The basic method for this medicine to work is by stopping the metabolic functions of the bacteria. Along with the use of Metrogyl 400 mg, the doctors will recommend a good diet, many exercises, and maintain an overall healthy lifestyle.

As there are different uses of the medicine, a patient should first consult with a doctor and be diagnosed. The doctor assesses the symptoms and gives different health checkup tests.

Key Information About Metrogyl 400 Mg

• Active ingredient– Metronidazole
• Purpose– To cure different bacterial infections completely.
• Used for treating Different bacterial infections
• Mechanism– Works by breaking the bacterial cell wall.
• Dosage– Given suitably depending on the type and severity of the infection.

Chemical Name

Metronidazole

Manufacturer

J B Chemicals and Pharmaceuticals Ltd.

What Metrogyl 400 mg is Used For

Doctors commonly prescribe it for:

• Amoebiasis (amoebic dysentery)

• Giardiasis

• Bacterial Vaginosis (BV)

• Trichomoniasis (a sexually transmitted infection)

• Dental infections (gum abscess, gingivitis)

• Root canal–related infections

• Post-surgical infections

• Skin and soft tissue infections caused by anaerobic bacteria

How Does The Metrogyl 400 Mg Work?

Metronidazole targets anaerobic bacteria and protozoa, which are types of germs that grow without oxygen.
By damaging their DNA, the infection gets cleared from the body.

• Slowly, as you keep using the medicine on time, it breaks the bacterial cell wall.
• This cell wall actually acts as a shield for the bacteria, protecting them from the outside environment.
• However, as soon as the cell wall breaks, the bacteria are exposed to the harmful outside environment.
• This stops the growth of the bacteria, finally giving you a cure to the infection.

How to Take Metrogyl 400

• Take it exactly as prescribed by your doctor.

• Usually taken 2–3 times a day, depending on the infection.

• Swallow with water; can be taken with food to reduce stomach upset.

• Complete the full course even if you feel better early.

How Is Metrogyl 400 Mg Used?

• Depending on your type and severity of the infection, the doctors can tell you to use the medicine up to three times per day.
• Use it with water and take the entire medicine at once without breaking it.
• Depending on your choice, you can take it before or after having some food.

Key Uses and Benefits

✓ Anaerobic Bacterial Infections:

Treats infections like pelvic inflammatory disease (PID), intra-abdominal abscesses, or dental infections caused by anaerobes.

✓ Protozoal Infections:

Effective against amoebiasis (Entamoeba histolytica), giardiasis (Giardia lamblia), and trichomoniasis (Trichomonas vaginalis).

✓ Other Indications:

Helicobacter pylori eradication (with other drugs for ulcers), bacterial vaginosis, or rosacea (topical form).

Strength And Substitute

There are other strengths of Metronidazole as we, ll like-

• Metrogyl 200 Mg (Metronidazole)
  Metrogyl (Metronidazole)
  Metrogyl Gel
  Metrogyl ER 600 Mg (Metronidazole)

Dosage

✓ Dose For Parasitic Infections

• Up to one medicine taken daily for mild issues for 1-2 months.
• Up to two medicines daily are taken for up to 3 or 4 months or even longer if needed.

✓ Dose For Other Anaerobic Bacterial Infections

• Up to a single medicine taken daily for 7 to 10 days for mild issues.
• Up to two medicines per day for up to 15 to 21 days if the infection is severe.

✓ For Dental Infections

Usually given in smaller doses like 50 mg or 100 mg for a few weeks.

✓ Dose For Children

Usually, smaller strengths are given to a child below the minimum permissible age limit of 8 years-

• For your child, the doctors may recommend any other smaller doses, like 25 mg or 50 mg.
• It also depends on the age and weight of the child, along with their other health conditions.

✓ Dosage Instructions To Patients-

• Making a routine of taking the drugs at the same time daily.
• Keep on using the medicine until the end of the tenure, even if the signs recover within a few weeks.
• Go for regular blood sugar checkups with your doctor.

✓ What Occurs If I Overdose On This Medicine?

Avoid exceeding the given dose or the tenure, or else some side effects can occur.

✓ What Occurs If I Miss Taking A Dose?

Do not miss taking your medicines on time, or else an inconsistent action may not help you to cure the infection totally.

Drug Interactions

Studies at the FDA show that the following types of medicines interact with Metrogyl 400 mg-

• Other antibacterials
• Anti-parasitic medicines
• Pills to cure nasal inflammation and allergies.
• Medicines to cure stomach ulcers and indigestion.

Side Effects

✓ Mild issues

• Headache
• Dizziness
• Fatigue
• Swelling of hands and feet

✓ Severe effects

• Severe diarrhea
• Indigestion
• Heartburn

Precautions And Warnings Before Taking It

✓ Precautions For Pregnant Women

• The Metrogyl 400 mg is generally not safe at the time of pregnancy.
• However, if the doctors feel that the condition of the disease is severe, with no alternative suitable remedy, they can allow you to use this medicine in some extreme cases.

✓ Caution Tips For Breastfeeding Mothers

• Use of the Metrogyl 400 mg is not safe as per an FDA report.
• While feeding, this may pass down to your infant, and that is certainly dangerous to their health.

✓ Caution Tips If You Are Prone To Dictions.

Doctors say that if you keep up your addiction habits, the medicine will not have any effect on curing your health at all. In addition, because of interactions, it increases the chances of a side effect.

✓ When Driving

• Use of the Metrogyl 400 mg pill is not safe if you feel any changes in your focus, concentration, or vision.
• These are some of the side effects of the medicine, which can increase the chances of a road accident.

Alternatives and Additional Tips

• Similar Medications: Tinidazole (Tindamax) for parasites, or clindamycin for anaerobes.
• Non-Antibiotic: Probiotics for gut health during treatment; hygiene for infections.
• Tips: Stay hydrated; eat yogurt to prevent diarrhea. Report persistent symptoms.

Warnings

Avoid taking with other health issues like-

• Heart blockage
• Kidney infections
• Abnormal liver functions
• Gastric disorders
• UTIs
• Urinary incontinence
• Nasal infections
• Anemia
• Cancer affecting your pancreas, heart, or kidneys.

Benefits

Use of the Metrogyl 400 mg pills helps to

• It cures different types of bacterial infections.
• It works both for adults and children, but in different strengths.

Safety Advice

Allergic tendency-

• Swelling of the mouth and lips
• Frequent infections and allergies

Avoid combining with other antibacterial medicines of the same type or composition.

Where Can You Buy Metrogyl 400 Mg In Australia?

Store the Metrogyl 400 mg in safe conditions in a sealed airtight container. The condition for storage must not be highly humid, or the temperature must not be above 30 degrees Celsius.

Summary

Metrogyl 400 is a powerful antibiotic used to treat a wide range of bacterial and parasitic infections. It’s effective, but must be used strictly under medical supervision, with alcohol strictly avoided during treatment.

Metrogyl 400 mg Tablet is an antibiotic used to treat several bacterial and parasitic infections. It is effective but must be taken exactly as directed, with strict avoidance of alcohol.

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