
Avanafil
Avanafil is an active ingredient used in prescription medicines for erectile dysfunction (ED) in adult men. It belongs to a group of medicines called phosphodiesterase type 5 (PDE5) inhibitors, which help increase blood flow to the penis during sexual stimulation.
This category features different Avanafil products and strengths for those looking to learn more about their available options.
What Is Avanafil?
Avanafil is an oral medicine prescribed to adult men who experience difficulty achieving or maintaining an erection suitable for sexual activity. It works by relaxing certain blood vessels and supporting blood flow into the penile tissues when sexual stimulation occurs.
Avanafil is also the active ingredient in Spedra, a branded ED medicine available in Australia. It is offered in different strengths, including 50 mg, 100 mg, and 200 mg tablets. The appropriate strength depends on individual response, health conditions, and other medicines being taken.
How Does Avanafil Work?
Avanafil works by blocking the action of an enzyme called phosphodiesterase type 5 (PDE5). This enzyme breaks down cyclic guanosine monophosphate (cGMP), a substance involved in relaxing smooth muscles and regulating blood flow.
When PDE5 activity is reduced, cGMP levels remain higher for longer. This allows the smooth muscles in the penis to relax, helping more blood enter the erectile tissues during sexual arousal.
A few points to understand about its action:
- It supports blood circulation in the penile tissues.
- Sexual stimulation is necessary for an erection to occur.
- It does not automatically cause an erection after taking a tablet.
- Its effect and duration can differ between individuals.
What Is Avanafil Used For?
Avanafil is prescribed for erectile dysfunction in adult men. This condition can make it difficult to achieve or maintain an erection during sexual activity.
By supporting blood flow during arousal, Avanafil can help men with ED respond to sexual stimulation. It does not increase sexual desire or treat the underlying causes of erectile dysfunction.
ED can be associated with several factors, including:
- Diabetes and related circulation problems.
- High blood pressure and cardiovascular conditions.
- Stress, anxiety and emotional concerns.
- Hormonal changes.
- Certain prescription medicines.
- Lifestyle factors such as smoking and excessive alcohol consumption.
A healthcare professional can assess these factors before deciding whether Avanafil is a suitable treatment.
Available Avanafil Strengths
Avanafil tablets are available in different strengths. The approved Spedra formulation in Australia comes in the following doses:
| Strength | General information |
| Avaforce 50 mg | A lower strength that may be considered when adjusting treatment. |
| Avaforce 100 mg | The usual recommended starting strength for many adult patients. |
The dose should be selected by a prescriber according to individual response and tolerability. A higher strength is not necessarily more suitable for everyone.
How to Take Avanafil?
Follow the instructions provided by your prescriber and the product information supplied with your medicine.
Keep these general points in mind:
- Avanafil is generally taken when needed before anticipated sexual activity.
- The recommended starting dose for Spedra is 100 mg, approximately 15–30 minutes before sexual activity.
- It can be taken with or without food, although food may delay its onset.
- Sexual stimulation is required for the medicine to work.
- Do not take more than one dose within 24 hours unless your prescriber has given different instructions.
Do not change the strength or frequency without discussing it with your prescriber.
Avanafil Side Effects
Like other PDE5 inhibitors, Avanafil can cause unwanted effects. Their frequency and severity may vary depending on the dose and individual response.
Common side effects:
- Headache.
- Facial flushing.
- Nasal congestion.
- Back pain.
- Dizziness.
Serious side effects:
Seek urgent medical attention if you experience:
- An erection lasting longer than four hours.
- Sudden loss or significant changes in vision.
- Sudden hearing loss.
- Chest pain or severe breathing difficulties.
- Signs of a serious allergic reaction, such as facial swelling or difficulty breathing.
Do not ignore unusual or persistent symptoms after taking Avanafil.
Precautions Before Using Avanafil
Before starting treatment, discuss your medical history and current medicines with your prescriber. This helps identify conditions or drug combinations that could increase the risk of unwanted effects.
- Heart and blood pressure conditions: Tell your prescriber if you have heart disease, an irregular heartbeat, low blood pressure or a history of stroke or heart attack.
- Kidney and liver problems: People with impaired kidney or liver function may require additional assessment before using Avanafil.
- Nitrate medicines: Do not combine Avanafil with nitrate medicines used for chest pain, as the combination can cause a dangerous drop in blood pressure.
- Other ED treatments: Avoid combining Avanafil with other PDE5 inhibitors unless specifically directed by a qualified prescriber.
- Alpha-blockers: Medicines used for prostate conditions or high blood pressure may increase the risk of dizziness and low blood pressure when taken with Avanafil.
- Alcohol: Drinking alcohol may increase the likelihood of dizziness, flushing and a drop in blood pressure.
- Driving: Avoid driving or operating machinery if you experience dizziness, vision changes or other effects that affect alertness.
At Australiarxmeds, you can explore available Avanafil products, compare their strengths and learn about their uses, possible side effects and precautions.
Understanding how Avanafil works and following the advice of a qualified prescriber can help you make informed decisions about erectile dysfunction treatment. Always check the product information and ensure that the medicine is suitable for your health needs before use.
Frequently Asked Questions
1. What is Avanafil used for?
Avanafil is prescribed to adult men to manage erectile dysfunction (ED). It helps increase blood flow to the penis during sexual stimulation, supporting the ability to achieve and maintain an erection.
2. How long does Avanafil take to work?
Avanafil is generally taken approximately 15–30 minutes before anticipated sexual activity. The time it takes to work can vary depending on individual response and food intake.
3. How long does Avanafil last?
Avanafil can support erectile response for several hours after taking a dose. Its duration varies between individuals and does not mean an erection will last continuously.
4. What are the common side effects of Avanafil?
Common side effects include headache, facial flushing, nasal congestion, dizziness and back pain. Serious reactions can include sudden vision or hearing changes and prolonged erections requiring urgent attention.
5. Can Avanafil be taken every day?
Avanafil is generally prescribed for use when needed before sexual activity. The maximum recommended frequency for Spedra is one dose within 24 hours. Follow the prescribed dosing instructions.
6. Is Avanafil available in Australia?
Yes. Avanafil is available in Australia as Spedra, a Schedule 4 prescription medicine. It comes in 50 mg, 100 mg, and 200 mg tablet strengths.
7. Can Avanafil be taken with other erectile dysfunction medicines?
Avanafil should not be combined with other ED medicines, such as Sildenafil or Tadalafil, unless specifically directed by a qualified prescriber. Combining these medicines may increase the risk of unwanted effects.

