Dr. Arjun Srivastav What Is Glycomet-GP 4 Forte (Metformin/Glimepiride)?
Glycomet-GP 4 Forte is a prescription antidiabetic medicine used to help control blood sugar levels in adults with type 2 diabetes.
Combination medication containing:
Metformin – reduces glucose production in the liver and improves insulin sensitivity
Glinide (e.g., Repaglinide or similar) – helps the pancreas release insulin faster in response to meals
Purpose: Improves blood sugar control, especially around meal times
Glycomet-GP 4 Forte is a drug used for the treatment of type 2 diabetes, usually when the same cannot be controlled with diet and exercise alone. Alone. It contains Glimepiride and Metformin as the two major ingredients.
It can also be used with some other anti-diabetic medications. You need to obtain this medication from the pharmacy with a prescription.
How Does Glycomet-GP 4 Forte (Metformin/Glimepiride)
Glycomet-GP 4 Forte is categorised under sulfonylurea, and it works by stimulating the beta cells inside your pancreas to increase insulin release. Insulin will move the sugar content from your blood to the cells of your body to generate energy.
It contains two major ingredients, and they work in the following pattern:
Metformin acts as a biguanide, which acts on the liver to reduce glucose production. It also delays the absorption of glucose from your intestine, which accumulates after a meal.
It induces more sensitivity to your body for using the insulin, so that the same amount can nourish the muscles effectively.
With Glimepiride, the blood sugar of your body is balanced and thus reduces the risks of diabetes. Thus, it can give protection against kidney damage, nervous issues, cardiovascular diseases, and blindness, which often result from high diabetes levels.
How It Works
Metformin:
- Reduces glucose release from the liver
- Improves how your body uses insulin
- Helps with weight control in many patients
Glinide (meal-time insulin stimulator):
- Stimulates the pancreas to release insulin
- Works quickly and briefly to manage post-meal blood sugar spikes
How Is The Glycomet-GP 4 Forte (Metformin/Glimepiride)?
Take Glycomet after your first heavy meal, probably breakfast. This helps the medicine to be absorbed easily and thus restricts stomach upset and a fall in BP.
Take the tablet whole and never chew or crush it. Swallow it with water. Never stop the course of medication before your doctor suggests you do. Consistency is very important to get the best benefits from Glycomet.
Who It’s For
Adults diagnosed with type 2 diabetes
When lifestyle changes (diet & exercise) alone are not enough
When both fasting and post-meal sugar levels need improvement
How to Take It
Usually taken before meals to control post-meal blood glucose
Take exactly as your doctor prescribes
Don’t skip doses or change doses without medical advice
Benefits
Better control of post-meal glucose spikes
Improvement in overall blood sugar (HbA1c)
Works in two different ways for more effective control
Dosage
- The right dosage of Glimepiride and Metformin combination is 1-2 mg a day, taken once a day. However, the doctor might gradually increase the dosage to 8mg a day.
- The dosage tenure must be decided by your doctor.
- And for children, the use of Glycomet is not preferred.
Overdose: Exceeding the prescribed amount can lead to serious complications like severe hypoglycemia and lactic acidosis. Immediate medical attention is necessary if an overdose is suspected.
What Occurs If I Overdose On Glycomet-GP 4 Forte (Metformin/Glimepiride)?
Overdosing on Glycomet means taking more than one pill a day, and this is not regarded as safe, as the same can lower blood sugar levels and can even cause fainting.
If mistakenly overdosed, consult your doctor immediately. He might suggest an ingestion of insulin to compensate for the overdose.
What Occurs If I Miss Taking A Dose?
Missing a dose of Glycomet can be compensated for if you take it within 4 hours of missing the intake. However, if you make more delay, then skip the day’s dosage.
Common Side Effects
Gastrointestinal: nausea, diarrhea, upset stomach
Low blood sugar (hypoglycemia): especially if meals are skipped
Weight neutrality or mild loss (often from the Metformin component)
Drug Interactions
- Should be avoided: Some medications, like Insulin, can make it troublesome for Glycomet to work properly, as both of them work in the opposite direction.
- Fatal fall of Blood pressure: Beta blockers like Atenolol can be dangerous with Glycomet. The same happens with Captopril, an ACE inhibitor. In both cases, blood pressure drops suddenly, which can result in fainting and even a stroke.
- Need Dosage Adjustment: Aspirin and warfarin react with Glycomet, and dosage adjustment is essential. MAOI drugs and antidepressants also affect blood sugar levels when taken with Glycomet, and dosage adjustment is essential. Clarithromycin must not be taken with Glycomet, or your doctor might adjust the dosage timing, as taking that with Glycomet can cause sugar levels that can be fatal.
- Medicines that reduce the effect of Glycomet: Contraceptive pills, Diuretics, Corticosteroids, thyroxine, and phenytoin.
- Lactic Acidosis: Alcohol, Cimetidine, and topiramate must be avoided strictly with Glycomet.
Precautions
Not suitable for people with severe kidney or liver impairment
Avoid alcohol (can increase side effects and risk of lactic acidosis with Metformin)
Inform your doctor about all other medicines you take
Important to monitor blood sugar regularly
Side Effects
Some of the side effects that you can find while using Glycomet can be major. Otherwise, there can be some general side effects too.
➦ Common Effects
- Appetite loss
- Metallic taste
- Pain in the stomach
- Headache
- Diarrhoea
- Dizziness
- Confusion
- Excessive sweating
- Infection in the respiratory airways
- Tiredness
➦ Intense Effects
- Excess lactic acid.
- Deficiency in Vitamin B12, causing anaemia.
- Jaundice
- Severe allergic reactions.
Precautions & Warnings
- Alcohol can cause hypoglycemia and lead tose life life-threatening condition due to increased lactic acid.
- Low blood sugar or Hypoglycemia.
- Always keep some candy, glucose tablets, or glucose-rich fruit juices to support a fall in blood sugar.
- A regular diet is essential. Have vitamin B12 (mutton or tablets) in regular intervals.
- Glycomet is not suitable for pregnant and lactating women. Consult your doctor and then only take Glycomet in such conditions.
- Liver and Kidney issues and their medications can disturb the medication with Glycomet. You must consult your doctor before taking both medicines together.
- Using Glycomet for a long duration can harm your liver (jaundice) or kidneys. It can absorb Vitamin B12 from your body. Hence, take such supplements regularly.
Benefits Of Taking Glycomet-GP 4 Forte (Metformin/Glimepiride).
- Glycomet-GP 4 Forte is very effective in the treatment of type 2 diabetes.
- In case your diet plan and exercises are not able to reduce your diabetes level, Glycomet is the best supportive pill.
- It can help to balance your blood sugar, and it is the best medicine to easily control the same.
- Side effects are well controllable if you follow the precautions and disclose your medical history to your doctor.
Where Can I Buy Glycomet-GP 4 Forte (Metformin/Glimepiride)?
Buy Glycomet-GP 4 Forte from Australiarxmeds, the best store of generic medicines to provide you with the fastest delivery service.
The store makes its stock directly from the TGA-approved manufacturers, and hence, a price rebate is ensured in every purchase.
Quick Summary
Glycomet-GP 4 Forte is a combination diabetes medicine that helps improve blood sugar control, especially around meal times, by combining metabolic and insulin-stimulating effects.
It should always be used under your doctor’s supervision along with lifestyle measures like diet and exercise.
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