Dr. Arjun Srivastav
Avanafil and Dapoxetine tablets combine two active medicines intended to address different male sexual health concerns. Avanafil is a PDE5 inhibitor used for erectile dysfunction (ED), while Dapoxetine is a short-acting SSRI used to help manage premature ejaculation (PE).
The combination is designed around two separate treatment needs rather than one ingredient performing both functions. Understanding the role, strength, administration, and safety considerations of each ingredient can help you make a more informed decision about the product.
At a Glance
| Product detail | Information |
|---|---|
| Active ingredients | Avanafil + Dapoxetine |
| Primary treatment areas | Erectile dysfunction + Premature ejaculation |
| Avanafil drug class | PDE5 inhibitor |
| Dapoxetine drug class | Short-acting SSRI |
| Intended use | When both ED and PE require treatment |
| Administration | Follow the specific product and professional instructions |
| Strength | Depends on the specific combination product |
What Are Avanafil and Dapoxetine?
Avanafil and Dapoxetine are two pharmacologically different medicines combined in certain tablets for men who require treatment for erectile dysfunction and premature ejaculation.
Avanafil works on the physiological process involved in penile erection. It helps improve blood flow to penile tissue during sexual stimulation by inhibiting the PDE5 enzyme.
Dapoxetine works within the nervous system. It belongs to the SSRI class and affects serotonin signalling involved in ejaculation control.
The combination therefore brings two distinct actions into one formulation. It should not be considered a general sexual-performance enhancer, and suitability depends on an individual’s health, medicines and treatment requirements.
Composition
The active ingredients are:
- Avanafil – the PDE5 inhibitor component.
- Dapoxetine – the short-acting SSRI component.
Tablets may also contain inactive ingredients, or excipients, required for manufacturing and tablet stability. These vary between manufacturers, so check the product packaging for the complete ingredient list.
Manufacturer
Manufacturer: Sunrise Remedies Pvt Ltd
Product: Super Avana
Active ingredients: Avanafil + Dapoxetine
Why Are Avanafil and Dapoxetine Combined?
These drugs serve different purposes when it comes to therapy, and this is the major cause of their possibility to be combined.
In some cases, a patient might face problems with erections and ejaculation control. In order to address both problems, different pharmacological actions are needed.
The first drug works by affecting the PDE5 pathway related to erections, whereas the second one influences serotonin signaling related to ejaculation control.
In this way, this drug combination provides two different therapies in one pill instead of using only one active substance to treat both disorders.
It is worth noting that a drug combination does not mean that it will definitely be better than a monotherapy. A physician can evaluate the necessity of using both substances based on your ED symptoms, health condition, and treatment.
How Do Avanafil and Dapoxetine Work?
Avanafil Mechanism
Avanafil belongs to a group of medicines called PDE5 inhibitors, which is a mediator of the degradation of cyclic guanosine monophosphate (cGMP).
Sexual stimulation leads to the production of nitric oxide, and its signaling pathway results in the rise of cGMP levels in penile tissues. The blocking of PDE5 by Avanafil allows cGMP to function normally, promoting relaxation of smooth muscle cells and an inflow of blood to the penis.
This mechanism is able to help to get an erection with sexual stimulation.
Avanafil does not induce sexual desire and erection without sexual stimulation.
Dapoxetine Mechanism
Dapoxetine is a short-acting selective serotonin reuptake inhibitor.
This drug works on serotonin activity in the nervous system through decreased serotonin reuptake, which could affect ejaculation processes in males suffering from premature ejaculation.
In contrast to Avanafil, Dapoxetine does not work via increased blood flow to penile tissue.
Avanafil and Dapoxetine Strengths
Combination products are available in different formulations, so the amount of each ingredient should always be checked separately.
For example, a product described as Avanafil and Dapoxetine 80 mg may contain:
Avanafil 50 mg + Dapoxetine 30 mg = 80 mg combined active ingredients.
The total figure does not necessarily represent the amount of Avanafil alone.
Other formulations may contain different proportions, such as:
Choosing a Strength
Having high strength numbers should not be taken as an indication of something better. Depending on various considerations like past response to the drug, medical history, and other drugs, the right formula needs to be chosen.
The individual strengths for Avanafil and Dapoxetine need to be verified always.
Avanafil and Dapoxetine Dosage
The appropriate dosage depends on the specific formulation and individual circumstances. Follow the instructions supplied with your medicine and the advice of your healthcare professional.
Before recommending a strength, a healthcare professional may consider:
- Existing medical conditions
- Cardiovascular health
- Blood-pressure status
- Other medicines being taken
- Previous response to treatment
- Liver function
- Kidney function
- Potential drug interactions
- Previous adverse reactions
Do not increase the amount because you believe a higher strength will provide a stronger effect.
Taking more than recommended can increase the likelihood of adverse effects without guaranteeing better results.
Missed Dose
If the medicine has been prescribed for use around anticipated sexual activity and you miss a planned dose, do not take extra tablets to compensate. Follow the instructions specific to your product.
Overdose
Taking more than the recommended amount may increase the risk of dizziness, headache, nausea, low blood pressure, fainting and other adverse effects.
If you believe you have taken an excessive amount, seek medical advice promptly.
How to Take Avanafil and Dapoxetine
Take the tablet according to the instructions provided for your specific product.
- Swallow the tablet with water.
- Follow the prescribed timing.
- Do not exceed the recommended amount.
- Do not take additional ED medicines unless advised by a healthcare professional.
- Tell your doctor or pharmacist about all medicines and supplements you use.
Avanafil works as part of the body’s natural erectile response and requires sexual stimulation.
Food can affect the absorption or timing of some medicines. Follow the product-specific instructions rather than assuming that every Avanafil and Dapoxetine formulation should be taken in exactly the same way.
Potential Benefits
The potential benefit of the combination comes from its two distinct pharmacological actions. Men exploring different medical approaches to erectile dysfunction can also learn more about how to treat erectile dysfunction with the best pills.
Support for erectile function
The Avanafil component may help men with ED achieve and maintain an erection when sexual stimulation occurs.
Support for ejaculation control
The Dapoxetine component may help men experiencing premature ejaculation improve control over ejaculation.
Two treatment actions
Using two active ingredients in one formulation can provide treatment directed at both erectile function and ejaculation control when both concerns have been medically assessed.
The response varies between individuals, and the medicine should not be used with the expectation of permanently curing either condition.
Avanafil vs Dapoxetine
| Feature | Avanafil | Dapoxetine |
|---|---|---|
| Drug class | PDE5 inhibitor | Short-acting SSRI |
| Main target | Erectile function | Ejaculation control |
| Primary action | Supports penile blood-flow response | Modifies serotonin signalling |
| Requires sexual stimulation for its primary effect | Yes | Not applicable in the same way |
| Direct treatment for ED | Yes | No |
| Direct treatment for PE | No | Yes |
This distinction is useful when comparing combination products with single-ingredient medicines.
What Avanafil and Dapoxetine Do Not Do
These medicines have specific treatment roles and should not be viewed as a universal solution for sexual health concerns.
- They do not directly increase sexual desire.
- Avanafil does not normally produce an erection without sexual stimulation.
- Dapoxetine is not a PDE5 inhibitor.
- The combination does not permanently cure erectile dysfunction.
- It does not permanently cure premature ejaculation.
- It does not provide protection against sexually transmitted infections.
- Taking a larger amount does not guarantee a stronger result.
- It should not be combined with another ED treatment without professional advice.
Understanding these limitations can help prevent inappropriate use.
Avanafil and Dapoxetine Drug Interactions
Tell your doctor or pharmacist about every medicine and supplement you use before starting treatment.
Nitrates
Avanafil should not be combined with nitrate medicines because PDE5 inhibition can contribute to a significant and potentially dangerous reduction in blood pressure.
Other ED medicines
Using Avanafil alongside another PDE5 inhibitor or ED treatment may increase the risk of adverse effects and blood-pressure changes.
CYP3A4 inhibitors
Certain medicines can interfere with the metabolism of Avanafil and increase its concentration in the body. Some medicines used to treat infections are examples of drugs that may require particular attention.
Serotonergic medicines
Dapoxetine can interact with medicines that affect serotonin, including certain antidepressants.
MAO inhibitors
Dapoxetine may interact with monoamine oxidase inhibitors and other medicines affecting serotonin pathways.
Alpha-blockers
These medicines may contribute to blood-pressure lowering or dizziness when used with Avanafil.
Alcohol
Alcohol can increase dizziness and fainting risk and may worsen some adverse effects.
This is not a complete interaction list. A doctor or pharmacist should review your medicines before treatment.
Side Effects of Avanafil and Dapoxetine
Side effects can vary depending on the individual and the medicines being used.
Precautions and Safety Advice
Cardiovascular health
Tell your doctor about heart disease, low blood pressure, uncontrolled blood pressure or recent serious cardiovascular events.
Mental health medicines
Inform your healthcare professional if you take antidepressants or other medicines that affect serotonin because of the Dapoxetine component.
Kidney or liver conditions
Existing kidney or liver problems may affect whether the medicine is appropriate for you.
Alcohol
Alcohol can increase dizziness and fainting. Follow professional advice about alcohol consumption while taking the medicine.
Vision or hearing changes
Seek medical attention if sudden changes in vision or hearing occur after taking Avanafil.
Previous allergies
Do not use the medicine if you have previously experienced a serious allergic reaction to Avanafil, Dapoxetine or any ingredient in the specific product.
Before Buying Avanafil and Dapoxetine
Before purchasing a combination product, check the product details rather than relying only on its name or total strength.
Check the active ingredients
Confirm that both Avanafil and Dapoxetine are listed and verify the individual amount of each.
Check the strength
A product labelled “80 mg” may represent the combined amount of two ingredients rather than 80 mg of Avanafil.
Check the manufacturer
Review the manufacturer’s name and product information supplied with the medicine.
Review the packaging
Check the expiry date, batch details, pack size and other information supplied with the product.
Consider medicine interactions
If you take medicines for heart conditions, blood pressure, depression or other conditions, ask a healthcare professional whether the combination is appropriate.
Where to Buy Avanafil and Dapoxetine in Australia?
When purchasing Avanafil and Dapoxetine online, review the product information carefully before ordering.
Check the active ingredients, individual strengths, manufacturer, pack size, and product information so you know exactly which formulation you are purchasing.
AustraliaRxMeds provides product information and purchasing options for Avanafil and Dapoxetine products. Review the available product details and consult a healthcare professional if you are unsure whether the medicine is suitable for you.
FAQs
Can a man take Avanafil and Dapoxetine with a kidney disorder?
Avanafil and Dapoxetine is not safe for recommendation in case of a patient suffering from severe kidney disease or infection.
Is Avanafil and Dapoxetine legal in Sydney?
Yes, using Avanafil and Dapoxetine has been made legal in Sydney after the TGA in Australia approved the compositions inside the medicine. Not only Sydney, but you can also get it across the country now.
Can I take Avanafil and Dapoxetine daily?
Yes, in case you have more severe ED, the doctors recommend using a daily pill to get consistent actions of the drug.
Is driving allowed after taking 10 mg Avanafil?
No, using any of these kinds of medicines that contain Avanafil in it can make you feel drowsy or have sleepiness.
Is Avanafil and Dapoxetine enough for ED?
Yes, the medicine is generally enough to get rid of ED for most patients. However, in case of a severe ED problem there are other higher strengths of the medicine for your use.
How long does Avanafil and Dapoxetine last?
As per studies and estimates done based on the dosage and substances present in the Avanafil and Dapoxetine pills, each medicine lasts about 7 to 8 hours. Each pill thus only gives you a form of temporary relief against the signs of ED and PE.
Can Avanafil and Dapoxetine help with premature ejaculation (PE)?
Yes, it contains the substance Dapoxetine that can give instant result on your early ejaculation issue.
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