Dr. Arjun Srivastav What is Sildenafil 50 mg?
Sildenafil 50 mg is a prescription drug for erectile dysfunction (ED) treatment in Australia. It is essentially a PDE5 inhibitor, and it provides help to males with impotence get an erection during sexual activity when they are sexually stimulated.
The drug is available in several other strengths, which are approved by the TGA, and therefore, there remains an advantage for dosage adjustment for the patients. Centurion Laboratories manufactures the formulation as Cenforce 50 mg, providing a cost-effective solution for ED management.
Composition and Appearance
Active Ingredient: Sildenafil Citrate
Inactive Ingredient: ADC Phosphate and Microcrystalline Cellulose as binders, Croscarmellose sodium for fast tablet break-up.
Appearance: Uncoated, round, blue coloured with debossing of 50 on one side and a breaking notch on the other side.
Note: Sildenafil 50 mg Australia is a prescription-only medicine. It must be obtained and used solely under the supervision of a qualified healthcare professional.
Onset of action
- Absorption: 30-60 minutes from intake.
- Peak Concentration: 30 to 120 minutes.
- Half time: 5 to 4 hours.
- Effectivity window: 4 to 6 hours.
What is sildenafil 50 mg used for?
Primary Use: Erectile Dysfunction (ED)
The most frequent use of Sildenafil 50 mg is to treat Erectile Dysfunction. Keeping those muscles relaxed, it allows more blood to flow into the area when a person is sexually aroused, helping to achieve and maintain an erection.
Secondary Use: Pulmonary Arterial Hypertension (PAH)
Under different brand names, Sildenafil is used to treat a serious condition called Pulmonary Arterial Hypertension, which is high blood pressure in the arteries of the lungs.
Important Note
The 50 mg dose is the standard starting dose for most adults. It does not cause an automatic erection; sexual stimulation is still required for the medication to work.
How does Sildenafil 50 mg Australia work?
PDE5 Inhibitor: Sildenafil 50 mg works to inhibit the enzyme that narrows the blood vessels, called phosphodiesterase type 5 (PDE5) inhibitor.
By inhibiting PDE5, Sildenafil helps in blood flow to the penis. Thus, it helps the penis to get the essentials it needs to get a hard erection.
Nitric Oxide Release: Sildenafil influences the release of Nitric Oxide, which increases blood flow to the penis, allowing the bloodstream to reach the penile tip, giving a hard erection to males.
Increase cGMP Level: The adequate release of Nitric Oxide helps to increase the level of cGMP, a monophosphate that relaxes and smoothens the penile veins. This relaxation aids in keeping the blood flow intact for hours, allowing long hours of erection in males without any pain.
How Long Does Sildenafil 50 mg Last?
Effects may last:
- Around 4 to 6 hours
This does not mean a constant erection for hours. Instead:
- The ability to achieve erections improves during this period when sexually stimulated.
Dosage of Sildenafil 50 mg Australia
Daily Dose
Never take more than one tablet within 24 hours. When you are taking the second dose of Sildenafil 50 mg, make sure that you have crossed 24 hours since you took the last dose.
Dose Timing: Take the dose 60 minutes before your sexual interaction. It will give you a hard erection, only when you are sexually aroused.
Food Preference: Empty stomach intake is preferable. However, in some cases, you can face nausea while taking the dose on an empty stomach. In such cases, take a light meal and then have the dose.
Age Barrier: Sildenafil is not prescribed in Australia to patients less than 18 years of age. The upper limit of age, according to guidelines of the WHO, is 64-65 years.
However, Cenforce 50 mg of Sildenafil is often prescribed to patients more than 50 years old after checking all other health aspects.
Missed Dose
If you miss a dose, you can take it without delay, but keep in mind not to take the drug with heavy meals, as that delays the action.
Overdose
Overdose is not preferable, as that can cause severe side effects like acute back pain, extreme dizziness, chest pain, loss of vision, and a fall in BP. Always keep two doses 24 hours apart.
Available Strengths of Sildenafil 50 mg Australia
- Sildenafil 100 mg
- Sildenafil Citrate Sublingual Tablets 100 mg
- Sildenafil and Tadalafil Tablet Australia
- Sildenafil Citrate Chewable Tablets 100 mg
- Sildenafil Oral Powder (Sildenafil Citrate)
- Sildenafil Fluoxetine Tablet
Tip
An appropriately strong dose should always be determined by a licensed healthcare provider based on individual patient response and tolerability.
Benefits of Sildenafil 50 mg Australia
Resolution from Impotence: Sildenafil is an approved drug and is one of the most preferred PDE5 inhibitors that gives relaxation from impotence and gives men a hard erection during intercourse.
Helps in Lowering Blood Pressure: The relaxation of blood vessels induced due to the release of cGMP helps in lowering blood pressure in males.
Brings back Confidence: It brings back the confidence in you, which you lost due to your impotence issue, and makes you compatible in bed.
Pleasure for Partners: Sildenafil provides 4 hours of a strong erection to males, helping them to ensure their own and their partner’s pleasure in their lives.
Stress Release: Impotence gives heavy stress to men in their personal lives. Sildenafil gives a solution for them to come out of the stress.
Sildenafil 50 mg vs. Sildenafil 100 mg - Comparison Table
| Feature | Sildenafil 50 mg | Sildenafil 100 mg |
|---|---|---|
| Typical Use | Standard/Starting dose | Maximum/Refractory dose |
| Success Rate | High for most users | Higher for "difficult" cases |
| Side Effect Risk | Moderate | Higher |
| Time to Work | 30–60 minutes | 30–60 minutes |
| Duration | Up to 4 hours | Up to 4 hours |
Drug Interactions
Interacting Drugs:
- Nitrates: Never take Nitrates with Sildenafil. Nitrates and poppers are drugs used for the treatment of angina, a heart condition. When Sildenafil interacts with it, it can cause acute chest pain or a severe drop in Blood Pressure.
- Alpha-blockers and Blood Pressure Reducers: Drugs that cause a drop in BP, either directly or indirectly, can cause issues when they interact with Sildenafil. If you already take such a type of drug, consult with your doctor about the safety factors before taking the drug.
- CYP3A4 inhibitors: Calcium channel Blockers like Verapamil, some antibiotics like erythromycin, are moderate inhibitors of the enzyme CYP3A4, while antifungals like ketoconazole and Protease inhibitors like Ritonavir come to this category of enzyme inhibitors. All these drugs increase the amount of Sildenafil in the blood, causing side effects.
Interacting Diseases:
- Severe Heart Condition: Patients having serious heart conditions, such as angina, chest pain, or who have undergone heart surgeries, like angioplasty or bypass surgery, must not take Sildenafil.
- Liver impairment: Patients with renal and liver issues must consult with their doctors before taking Sildenafil as a daily dose. Your doctor might conduct some tests to check your renal and liver condition before prescribing you the Sildenafil 50 mg tablet.
- Retinal Issues: Since Sildenafil reduces blood pressure, it can affect your eyes or hearing. When you have existing issues with those, it can result in temporary loss of vision or hearing impairment.
Interaction with Food:
- Alcohol and Grapefruit: Both of them can increase light-headedness and dizziness in patients taking Sildenafil 50 mg Oral Tablet. Moreover, they can be toxic to the liver. Therefore, avoiding these two items while taking Sildenafil is the doctor’s choice.
- Heavy Meals: Prefer to take Sildenafil on an empty stomach. If you face nausea while doing so, try with a light meal. However, never take heavy meals as that delays absorption of the drug.
Side Effects of Sildenafil 50 mg
Common Side Effects
- Headache and light headedness: Extreme lowering in Blood Pressure can cause such side effects. You must take enough water and always avoid alcohol to avoid such issues.
- Nausea and Diarrhoea: If you face nausea with Sildenafil, try taking a light meal before taking the drug. If you face Diarrhoea, strictly avoid heavy or fat-included meals before taking the drug.
- Fall in BP: Sildenafil eases blood pressure by relaxing the blood vessels. If you take some other blood pressure reducing medicines, stop them or consult with your doctor about their dosage and timing.
- Back pain: Usually, this is a symptom of overdosing. Never take two Sildenafil tablets within 24 hours.
Rare and Serious Side Effects
- Chest Pain: If you have existing heart disease, you can face such issues. Never take nitrates or poppers with Sildenafil.
- Sensory Issues: Hearing Impairment or loss of vision, if faced, reach your doctor immediately.
- Renal Issues: In case you are taking some enzyme inhibitors or have some existing renal issues, take Sildenafil only after consultation with a doctor to avoid these issues.
- Priapism: In case you find a painful erection lasting more than 4 hours, immediately talk to your doctor regarding this. Delays can even lead to surgery.
sildenafil 50 mg Precautions and Warnings
Driving: Sildenafil causes mild to acute dizziness, which is very unsafe for driving or working on accident-prone machines.
Food Preference: Heavy meals delay the onset of Sildenafil, while alcohol causes extreme dizziness, which is toxic to your liver.
Heart Condition: Sildenafil, when taken with a poor heart condition, can even cause a stroke or a heart attack. Avoid sildenafil 50 mg when you take heart disease medication regularly or when you have a history of undergoing angioplasty.
Interactive Drugs: If you are taking any of the drugs that interact with Sildenafil, first consult the same with your doctor, allow him to adjust your doses and drug timings, and then take Sildenafil.
Warning
Do not take Sildenafil at any dose if you use nitrate medications (like nitroglycerin for heart problems). This combination can cause a sudden, life-threatening drop in blood pressure.
When not to use Sildenafil 50 mg tablet?
- Poor Heart Condition: If you have a poor heart condition with a history of angioplasty or angina, never take Sildenafil.
- If you are underage: Patients below 18 years of age must not take Sildenafil.
- If You are Allergic: If you are allergic to Sildenafil, avoid taking the drug.
Storage
- Temperature: Store Sildenafil 50 mg at room temperature. 25⁰C to 30⁰
- Avoid: Avoid moist, freezing, and direct exposure of the drug to sunlight.
- Safety: Keep the drug away from Kids and Pets.
Where to buy Sildenafil 50 mg in Australia?
Always buy sildenafil 50 mg from an authentic and TGA-approved online pharmacy like Australiarxmeds. Get an additional discount and delivery service to all locations in Australia as you make your purchase from there.
FAQs
How much time does it take to give me arousal?
As you take the drug, it will take approximately 60 minutes to give you an erection, provided that you have not taken the pill with a heavy meal. Note that the drug can only give you an erection when you are sexually stimulated.
Can Women take the Sildenafil 50 mg drug?
Sildenafil tablets will not give any sexual aid to a woman when they take them. Instead, side effects like nausea or diarrhoea can be seen in them. According to the TGA, men above the age of 18 can take the drug.
How can I get a fast erection with Sildenafil?
You will have to be sexually stimulated as Sildenafil does not work on your libido. You must take the drug 60 minutes before intercourse. Always avoid heavy meals.
When must I avoid Sildenafil 50 mg Australia strictly?
When you are less than 18 years old and when you have a serious heart condition, avoid Sildenafil in these two conditions.
