What is Moxibow 400mg?
The 400 mg Moxibow tablet is an effective prescription antibiotic used mainly for the treatment of serious or advanced bacterial infections. The drug forms a unique group of antibiotics known as fluoroquinolones (fourth generation fluoroquinolones).
Primary use of Moxibow 400mg:
Moxibow 400 mg provides broad-spectrum protection against different types of bacteria like-
- Gram-positive
- Gram-negative
- Anaerobic
- Atypical bacterial pathogens
This drug is frequently used by doctors to treat difficult infections that occur within specific areas like the sinuses, lungs, airways, abdomen, and deep layers of the skin tissue.
Composition and Appearance
- Active substance: Moxibow with each pill an exact 400 mg of the substance is the only substance inside the medicine.
- Physical Description: Moxibow 400mg is a distinctive, pink coloured, capsule shaped, biconvex tablet with a beveled edge. It has a smooth and unmarked surface on one side while there is a distinctive “MF” imprint on the other side. Its dimensions are about 17 mm long and 8 mm wide.
Manufacturer
Moxibow 400mg is produced and distributed under strict international regulatory guidelines by Biochem Pharmaceutical Industries Limited
Onset of Action
Moxibow 400mg is formulated for fast absorption into the bloodstream of humans when taken orally.
- Maximum Blood Concentration: it peaks inside your blood within 1 to 2.5 hours after use.
- Symptom Improvement: it will take about 24 to 48 hours to start feeling a reduction in symptoms.
- Important Point: If you find that you have lost all of your physical symptoms after 2 days, the biological infection does not necessarily mean that it has been eliminated. It is important for you to follow the full course recommended by your doctor.
How it Works (Mechanism of Action)?
- Due to its ability to bind strongly to both of the above enzymes, Moxibow makes the bacteria ineffective in repairing, duplicating, or copying its own genetic code.
- As such, without dividing or even maintaining structural stability, the bacteria cells will burst and die.
- The fact that this drug is capable of blocking both enzymes mean there is little chance of the bacteria developing resistance through one single mutation.
Dosage Guidelines
Moxibow 400 mg is a highly potent antibiotic. It should only be taken in accordance with the prescription of a qualified medical practitioner.
Standard Dose for Adults:
The usual dose prescribed for adults suffering from infection is one 400 mg pill per day.
Administration Tips:
You may take this pill whether you eat or not. Taking the pill together with a full glass of water is helpful for better absorption. In order to maintain the constant level of the medication in your body tissues, it is recommended that you take it regularly.
Duration of Therapy: The total time is dependent entirely upon the site of infection and its seriousness:
- Acute Bacterial Sinusitis: 5 to 7 days
- Worsened Chronic Bronchitis: 5 to 10 days.
- Community Acquired Pneumonia: 7 to 14 days.
- Complicated Skin and Soft Tissue Infection: 7 to 21 days
- Pelvic Inflammatory Disease: 14 days of uninterrupted treatment
Benefits of Moxibow 400mg
Choosing Moxibow 400mg gives the following distinctive clinical benefits compared to historical antibiotics:
Well Rounded Spectrum Reach:
It is capable of handling diverse bacterial settings, which may need several alternative drugs for treatment.
High Penetration into Target Tissues:
The drug has an excellent penetration into human tissues, creating high levels of protection within respiratory mucus, lung tissues, alveolar fluid, abdominopelvic cavities, and skin.
Convenient Once-a-Day Administration Schedule:
With the high half-life, there is no need to keep up with complicated multi-dosing schedules, leading to better overall patient compliance.
Lower Resistance Patterns:
Due to the double enzyme inhibition, it ensures continued clinical effectiveness even against strains resistant to old penicillin or Cephalosporins.
Drug Interactions
Antacids and Mineral Supplements:
Mineral supplements that include magnesium, aluminium, calcium, iron, or zinc bind with Moxiflacin directly in the GI tract, making it absorbable. You should take Moxibow 4 hours before or 8 hours after the intake of these mineral products.
QT-Prolonging Drugs:
The use of Moxibow together with either Class IA or Class III antiarrhythmic drugs (for example, Amiodarone, quinidine, and Sotalol), tricyclic antidepressant drugs (such as amitriptyline.
Oral Anticoagulants (Warfarin):
Moxibow has the potential to increase the anti-clotting effects of Warfarin leading to excessively high INR levels within the body.
Corticosteroids (Prednisolone):
This combination increases the physiological hazard associated with tendonitis and the rupture of the tendons.
Diabetes Drugs:
This could result in erratic fluctuations in blood sugar levels.
Side Effects
Just like all strong medication, Moxibow 400mg is bound to bring about some side effects. Some are minor while others need immediate attention.
Common Side Effects (Mild)
- Nausea, mild diarrhea, or abdominal pain
- Headaches or momentary dizziness
- Light-headedness or difficulty sleeping during the night.
- Temporary overgrowth of fungus in the mouth and vagina because of bacterial balance
- Problems with the stomach such as digestion and bloating
Side Effects (Require Immediate Medical Assistance)
- Tendonitis and Tendon Rupture: Swelling around the wrist, heel, and shoulder.
- QT Interval Prolongation: Dizziness, fainting, and faster heartbeat
- Peripheral Neuropathy: Burning tingling sensation on the palms and feet.
- Gastrointestinal Symptoms: Most of the time the patients can get diarrhea.
Precautions and Warnings
Sunlight Sensitivity (Photosensitivity):
Avoid going under the sun or taking necessary steps like using sunscreen, wearing protective clothes as your skin may burn or irritate under direct sunlight.
Hydration Numbers:
Keep taking enough amounts of water throughout the day to help flush out the medicine on time from your body.
Drive and Operate Machinery:
in case you are feeling dizzy or have a headache, avoid car driving or operating with machines.
Risks of Aortic Aneurysm:
Fluoroquinolones has a risk of enlarging or even rupturing the major heart artery. It is always a good idea to inform the doctors if you have aortic aneurysm any other kind of heart disorder.
When Not to Use (Contraindications)
Hypersensitivity:
In the case you have any allergic tendency with Moxiflacin, inform it to the doctors or else you will have hives, and other hypersensitivity issues.
Age Limitations:
The minimum age you have to be is more than 18 years to safely take this medicine.
Pregnancy and Lactation:
It is contraindicated for use during pregnancy, conception, and breastfeeding since it may pass into the breast milk and cause damage to the baby’s bone formation.
Myasthenia Gravis:
Moxibow has an extremely dangerous effect on neuromuscular weakness and causes life-threatening respiratory insufficiency in patients suffering from this neuromuscular condition.
Existing Cardiac Abnormalities:
Refrain from use in case of existing conditions like hypokalaemia, long QT syndrome, and bradycardia that are not corrected.
Storage and Disposal
- Storage Conditions: Always keep under normal room temperature within 30 degrees Celsius. Look for places away from direct sunlight and avoid keeping near open windows or close to ovens or microwaves.
- Procedure for Disposing: It is never advisable to dispose of any unused or expired antibiotics in the home toilet or throw them away in the open trashcans. Seek guidance from your local drugstore about taking back your drugs for disposal safely.
Where to Buy Moxibow 400mg in Australia
Moxibow 400 mg is available in Australia with a prescription. If you live in Australia and want to purchase Moxibow 400 mg online, you can purchase them through Australiarxmeds.
