Metatile 5 Mg (Melatonin)

Last Updated on 05/16/2026 ✔ Medically Reviewed by Dr. Arjun Srivastav

What is Metatile 5 mg?

Metatile 5 mg is a type of supplement that helps you to have regular sleep time at night. This supplement is generally given only for a short term in the following issues-

• Jet lag
• Mild to severe insomnia
• Circadian changes due to changes in work shifts

This supplement begins to take its effects by increasing the activity of the nerve cells or neurons. Remember that the Metatile 5 mg is a generic brand. It is for use in patients only, as per the recommendation of the doctors.

Composition and Appearance

• Active Ingredient: Melatonin, which is a type of natural body hormone, is the generic compound inside the Metatile 5 mg.
• Inactive ingredients and excipients: There are standard medical binders and fillers inside the medicine, but these do not act inside the body to generate any kind of nootropic effects.
• Appearance: The pill comes in white color with a film coating and is circular in shape.

Manufacturer

HAB Pharmaceuticals & Research Ltd is the drug company in India for manufacturing this brand name.

Onset of Action

• Beginning of action: After studies, it has been found that the onset of action usually occurs within an hour in most patients.
• Lasting time: Metatile 5 mg, being a high dose, usually lasts for the entire nighttime if you take it in the early hours right after dinner. Studies find it to be effective for around nine to 10 hours easily.
• Onset of effects: It usually takes effect within 3 to 4 days of regular use.

How does Metatile 5 mg work?

Blocking Wakefulness Signals: The substance acts on certain MT1 and MT2 receptors located in the suprachiasmatic nucleus (SCN), which acts as the master clock in your brain. Acting upon these receptors prevents the signaling processes that maintain wakefulness.

Reducing Body Temperature: It causes the body to feel drowsy by reducing its core temperature slightly. Your brain automatically perceives this as an indication to enter the sleep phase.

Reducing Light Sensitivity: The substance affects the retinas in your eyes to reduce their sensitivity to the light present in the environment.

How to Take Metatile 5 Mg

Method to use: Simply swallow the pill with water and take it completely. Take it a few hours before your normal bedtime to have regular sleep.

With or without food: taking Metatile 5 mg on an empty stomach is better for faster absorption. However, most patients are not able to adjust to it, which is why the doctors recommend you only take a light meal.

Dosage and Administration of Metatile 5 mg

Dosage

The dosage of Metatil 5 mg is determined based on how severe the condition is or what the patient’s body can tolerate.

Missed dose

Being irregular about taking your dose may not allow you to get enough sleep at night. Continuing use of supplements is important to gradually normalize your sleep routine at night within a few days.

Overdose

If the dose of Metatile 5 mg tablet does not suit the health of a patient and is found to be in excess, it will surely end up affecting the health of the patient.

Benefits of Metatile 5 mg Tablet

Helps You Fall Asleep Faster: It makes it easier to go from being wide-awake to falling asleep, which is great for people who take a while to drift off.

Eases Jet Lag: It helps your body adjust to a time zone quickly, so you do not feel tired, grumpy, or get stomach problems when you travel.

Helps Night Workers: It assists those working on night shifts or rotating shifts in getting their sleep during the day by deceiving the body that it is nighttime.

Fixes Sleep Schedule: It helps those who usually sleep late and struggle getting out of bed in the morning. It does so by fixing their body’s natural sleep schedule.

Drug Interactions with Metatile 5 mg

With CNS depressants: Other medicines for sleep, sedatives, like Clonazepam and Alprazolam, can severely increase sleepiness and drowsiness. It can also risk you having severe issues like respiratory issues and motor neuron impairment.

CYP1A2 Inhibitors: Medicines like Fluvoxamine and Ciprofloxacin can increase the drug effects, causing morning sleepiness and drowsiness issues.

Anticoagulants and antiplatelet pills: medicines like warfarin and Aspirin can increase bruising or internal bleeding risks.

BP medicines like Amlodipine: Such medicines can reduce their effects under the effects of Metatile drugs.

Diabetes medicines: Doctors can check if the patient is taking any medicine or insulin injections, as Melatonin can alter metabolic signals and cause fluctuations in blood glucose.

What Are the Side Effects of Metatile 5 mg?

➦ Common Effects

• Headache, Dizziness: You may feel dizzy or have a headache after getting up from sleep in the morning. Notice of such issues lasts longer or gets intense, in which case you need to consult with a doctor.
• Fatigue: general fatigue can start to occur after taking the medicine or last in the morning after waking up. Take a rest for a few minutes or do mild stretching to get rid of it.
• Drowsiness: Avoid driving or doing any major activities during this time, particularly where there is a risk of injury or accident.
• Palpitations: See if you have signs of nervousness or sweating, in which case you can consult a doctor.
• Flushing: Notice signs of slight fever, or warmth on the chest, face, and palms, and splash water or apply a cold compress. If such issues get intense, talk with your doctor.

➦ Intense Effects

• Feeling suicidal thoughts: Avoid taking the medicine if you have feelings of self-harm and suicide, and immediately report such issues to the doctor.
• Oversleep: Visit the doctors and ask them to reduce the dose of possible.
• Signs of changes in behavior: Notice any signs of agitation, excessive anger, sudden outbursts, and emotional lack of control, and in all these issues, stop taking the medicine for further consultation with your doctor.

Warning and precautions

• Avoid Daytime use

Avoid use during the day, or else you may feel really sleepy and drowsy during your work hours.

• Do not use Supplements

Do not combine it with other supplements like brain stimulators, or else it can cause side effects. It is not safe to use this supplement for long-term use, usually more than a few weeks, since it can be habit-forming.

• Regularity

Use the dose daily at the same time. Keep using the same dose as given in your prescription.

• Pregnancy

In case you are pregnant, the doctors may recommend a smaller variant for you and even reduce the tenure for use to avoid harm to your health or the fetus.

• Breastfeeding

Studies find that use of Metatile 5 mg over a few weeks can cause the effects of the supplement to pass on to your breastmilk and is thus harmful to your baby.

• Addictions

Any kind of addiction is not safe with Metatile 5 mg because it reduces the effectiveness of the pill. In addition, it also interacts with the supplement, increasing the chances of side effects

• Driving

Remember that the effects of the pill can also create a few side effects, like dizziness, which can make it difficult to drive.

When not to use?

Other health issues: The TGA in Australia, through its research over the years, has found a few patient conditions to not suit the effects of the supplement, like-

• Severe depression or anxiety
• Heart blockage or right after a heart surgery
• With severe liver or kidney disorders

In case of rare and severe side effects: Seeing signs of aggression, or suicidal thoughts, which are rare side effects of the pill. These side effects should immediately alert the patient to seek help from the doctors and stop using the supplement from the next day onwards.

Signs of anaphylaxis: In some rare cases, less than 1%, it has been found that the patient is generally allergic to the supplement itself. Using it despite this can cause some systemic and rare uncontrolled side effects, like-

• Rashes or skin hives
• Difficulty breathing
• Problems to swallow
• Inflammation of the throat, face, and lips

Storage and disposal guidelines

Store the supplement in your bedroom in a locked cupboard to avoid children getting hold of the supplement and to avoid extreme heat and humidity. Dispose of unused medicines once the expiry date arrives.

Where to buy Metatile 5 mg in Australia?

The drug governing authority in Australia has only given rights to Australiarxmeds, an online supplement portal, to sell such prescription pills.