Cabgolin 0.5 Mg

What Is Cabgolin 0.5 Mg?

Cabgolin 0.5 Mg is a prescription medicine that belongs to the class of Dopamine Receptor Agonist class. The active ingredient in it is Cabergoline, and it treats high levels of prolactin in the body, called Hyperprolactinemia. The primary uses of the medicine are:

• Hyperprolactinemia: The excess prolactin in the body causes infertility, disturbance in menstrual cycles and unwanted production of breastmilk.
• Suppressing Lactation: Stopping breastmilk production after miscarriage or abortion.
• Prolactinomas: A tumour in the pituitary gland releasing excess prolactin.
• Parkinson’s Disease: Used as a second-line treatment to balance the movement in case of Parkinson’s.

➤ Manufacturer:

Sun Pharmaceutical Industries Ltd, the reputed TGA-approved manufacturing company of India, is the manufacturer of Cabgolin 0.5 mg.

➤ Composition And Appearance:

• Active Ingredient: Cabergoline
• Inactive Ingredients: Leucine and Lactose.
• Appearance: Oval-shaped white tablet with debossed marking, 0.5.

➤ Onset Of Action:

Pharmacological Onset:

• Prolactin Reduction: Within 3 hours of intake.
• Peak Effect: Between 48 and 120 hours of intake.
• Half Life: 63 to 69 hours.

Clinical Onset:

• Ovulation: It takes a few weeks or months to regularise the menstrual cycle.
• Galactorrhea: To stop unwanted milk production, it takes 1-2 weeks from the initiation of the drug.
• Tumour Treatment: It takes 3-6 months to shrink the tumour.

How Does Cabgolin 0.5 Mg Work?

Cabergoline acts like dopamine, the chemical messenger in the brain. It stimulates dopamine receptors in the pituitary gland, which releases prolactin. By doing so, it brings down the hormone level to the normal range.

Dosage Of Cabgolin 0.5 Mg:

Standard Dosage Details:

• Starting dose: 5 mg every week.
• Other Practice: Split the tablet into two halves and take them on Monday and Thursday of a week.
• Maximum dose: Doctors can prescribe you to take a maximum of 4.5 mg a week. However, the frequent practice for serious cases is 2 mg a week.

Use-specific Dosage:

• Inhibit Lactation: 1 mg (two tablets of 0.5 mg) taken once on the first day of the delivery.
• Tumour Treatment: 25 ng after every 12 hours for 2 consecutive days.
• Parkinson’s Disease: 2mg to 4.5 mg a week.

Missed Dose:

• Take the missed dose as soon as you remember it, but skip the dose if it is already time for the next dose.

Benefits Of Cabgolin 0.5 Mg:

• Restores Menstrual cycles: The drug fixes the issues that are causing irregular menstrual cycles and refixes the ovulation cycle in women, helping them to regain their fertility.
• Shrinks Tumours: It helps a lot in shrinking the tumours that secrete prolactin. The tumours are usually found in the pituitary gland, and they cause headaches and issues with your vision.
• Galactorrhea management: Unwanted and spontaneous milk production is stopped, giving you emotional support.
• Treats Hormonal imbalance in Men: High prolactin in men can lead to a reduction in testosterone, which causes issues in the fertility of men. Cabgolin helps men in this aspect.
• Protects Bone Density: Low estrogen or testosterone can affect the bone density in both men and women, called osteoporosis. Cabgolin normalizes these levels.

Drug Interactions:

• Antipsychotic drugs: Antipsychotic drugs are Dopamine antagonists, and they can cancel out the effect of Cabergoline. Therefore, avoid drugs like risperidone or haloperidol.
• Anti-nausea Drugs: Drugs like Reglan can stop Cabgolin from working.
• Blood Pressure Medicines: Antihypertensives, reacting with Cabgolin can cause an abrupt fall in BP. Beta-blockers, diuretics, and ACE inhibitors come into the category.
• Antibiotics: Macrolide Antibiotics can increase Cabergoline concentration in the blood to cause some side effects. Consult a doctor before taking Azithromycin or Clarithromycin.
• Other Ergot Derivatives: Cabergoline itself is an Ergot Derivative. When taken with other such drugs, side effects can increase. Ergotamine and Methylergonovine are examples of such medicines.

Side Effects:

Common Side effects:

• Nausea: Take the pill with lunch if you face such issues.
• Drowsiness: Never drive a car or work on a big machine with this drug.
• Dizziness: Stand up slowly when you are sitting, otherwise you can experience a sudden shift in vision or body balance.
• Fall in Blood Pressure: Avoid alcohol and drink plenty of water.

Serious Side Effects:

• ICD: Impulse Control Disorder is a very rare but critical side effect of Cabergoline. A person in such a condition can show extensively increased Sexual Stimulant, can have a motivation towards spending money and gambling.
• Fibrosis: Heart valves, Lungs, and abdominal lining can thicken, causing chest pain or a persistent cough.
• Hallucinations: It is common with higher doses, but with a 0.5 mg dose, it is very rare.
• Vision issues: Usually caused when blood pressure drops too much. See a doctor if facing such issues.

Precautions And Warnings:

Major Precautions:

• Heart Valve Disorder: Do not use the medicine if you already have issues with the heart valve. Cabergoline thickens the heart valves.
• Fibrosis: Fibrosis can also thicken layers of the lungs and abdomen. You can face chest pain, backpain or a dry cough in such cases.
• Mental Health Issues: Patients with a history of mental health issues like anxiety or depression must use the drug much carefully, as cabergoline can induce issues with their mental health.

Precautions of activities:

• Driving: Cabergoline reduces blood pressure. A combination of it with some beta blockers can cause several issues, such as blurred vision. Never drive a car when you take cabergoline.
• Impulse Control: You can face issues like interest in gambling, binge eating, or excessive sexual desire. If you face so, inform your doctor immediately.

Precautions for Special Population:

• Pediatric Use: TGA guidelines mention that cabergoline’s use is safe for children above the age of 16 years.
• Pregnancy and Breastfeeding: Breastmilk production will be stopped. Therefore, if you are feeding breastmilk to an infant, do not take Cabergoline. If pregnancy is confirmed, discontinue taking the drug.
• Elderly Patients: Use of Cabergoline in patients above the age of 65 can cause renal or liver issues.

When Not To Use:

• Hypertension: If you are suffering from hypertension, Cabergoline can cause fluctuation in your BP.
• Heart Valve Issues: Cabergoline thickens heart valves, causing serious heart issues. Only take the drug when the doctor confirms taking it after conduction echocardiogram. The same is the case with any history of fibrosis.

Storage And Disposal:

Store Cabergoline at room temperature and avoid moisture or direct sunlight. Keep it away from pets and kids.

Where To Buy Cabgolin 0.5 Mg In Australia?

Australiarxmeds is the safest place to buy Cabgolin 0.5mg. You need to show your prescription at the time of purchase and get a discount on each purchase.