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Azathioprine 75 mg is an immunosuppressant that reduces the activity of the immune system and is prescribed for certain medical conditions. Its use requires an individual treatment plan, regular monitoring and care with other medicines.

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Active-Ingredient Azathioprine
Indication Prevention of organ rejection in transplant patients, Rheumatoid arthritis
Manufacturers
Packaging 10 tablets in 1 strip
Strength 75mg
Delivery-Time 6 To 15 days
Mg 75mg
No-Of-Tube 120 Tablet/s, 30 Tablet/s, 60 Tablet/s
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Active-Ingredient Azathioprine
Indication Prevention of organ rejection in transplant patients, Rheumatoid arthritis
Manufacturers
Packaging 10 tablets in 1 strip
Strength 75mg
Delivery-Time 6 To 15 days
Mg 75mg
No-Of-Tube 120 Tablet/s, 30 Tablet/s, 60 Tablet/s

Azathioprine 75 mg is an immunosuppressant that reduces the activity of the immune system and is prescribed for certain medical conditions. Its use requires an individual treatment plan, regular monitoring and care with other medicines.

Last Updated on ✔ Medically Reviewed by Dr. Arjun Srivastav

What Is Azathioprine 75 mg?

Azathioprine 75 mg is an immunosuppressant medicine that helps control immune activity when it contributes to a medical condition or threatens a transplanted organ. The 75 mg strength stated on this product page should be confirmed against the product packaging and prescribing information.

75 mg of Azathioprine may be prescribed for conditions such as rheumatoid arthritis and to help prevent organ transplant rejection. The reason for treatment, the dose and the length of treatment depend on the patient’s circumstances and their specialist’s advice.

What Is Azathioprine 75 mg Used For?

Azathioprine may be prescribed when reducing immune-system activity is part of the treatment plan. Its uses include the following.

  • Rheumatoid arthritis: It may help control inflammation in selected patients when the treating specialist considers it appropriate.
  • Organ transplant care: It may be used with other medicines to reduce the risk of the immune system rejecting a transplanted organ.
  • Other autoimmune conditions: Depending on the diagnosis, it may be prescribed for certain conditions affecting the digestive system, skin, muscles or blood.

Not every patient with these conditions will need this medication. The choice of treatment depends on the diagnosis, previous treatment, response to other medicines and the clinician’s assessment.

How Does Azathioprine 75 mg Work?

75 mg of Azathioprine interferes with processes that immune cells use to grow and multiply. This reduces some immune responses that contribute to inflammation or cause the body to attack a transplanted organ.

The medicine does not usually provide immediate relief. Its benefits may take several weeks or months to become noticeable, depending on the condition being treated. Do not increase the dose because symptoms have not improved quickly; discuss your progress with your treating clinician.

How Long Does Azathioprine Take to Work?

The time needed to notice an effect varies with the condition and the individual treatment plan. Some patients may need to take it for weeks or months before its full benefit becomes clear.

Your doctor will assess how well the treatment is working and whether any changes are needed. Continue taking it as prescribed unless your healthcare professional advises otherwise.

Azathioprine 75 mg Side Effects

Not everyone experiences side effects, and their severity can vary. Azathioprine 75 can affect the digestive system, blood cell production, liver function, and the body’s ability to fight infections. Some changes may only become apparent through blood tests.

🟢 Common Side Effects

🔴 Serious Side Effects

🟢 Common Side Effects

Nausea or vomiting after taking the medicine
Diarrhoea or stomach discomfort
Unusual tiredness or weakness
Dizziness or light-headedness
Reduced appetite

🔴 Serious Side Effects

Unusual bruising or bleeding
Fever, chills or a persistent sore throat
Yellowing of the skin or eyes and severe or continuing abdominal pain
A severe rash, blistering, or peeling skin
Difficulty breathing and swelling of the face, lips, tongue, or throat
Nausea or vomiting after taking the medicine
Unusual bruising or bleeding
Diarrhoea or stomach discomfort
Fever, chills or a persistent sore throat
Unusual tiredness or weakness
Yellowing of the skin or eyes and severe or continuing abdominal pain
Dizziness or light-headedness
A severe rash, blistering, or peeling skin
Reduced appetite
Difficulty breathing and swelling of the face, lips, tongue, or throat

This list is not exhaustive. Contact your healthcare provider about new or unusual symptoms, even if they are not listed here.

How to Take Azathioprine 75 mg

Follow the directions on your prescription and the instructions supplied with your specific product. Do not change the dose or stop treatment on your own.

  • Take the prescribed amount at the times recommended by your doctor.
  • Swallow the tablet with water, following the instructions for the particular formulation.
  • Take doses consistently according to your prescribed schedule.
  • Check the product instructions about food and milk. Some Australian product information advises taking tablets at least one hour before or three hours after food or milk.
  • Do not crush, split or chew the tablet unless a doctor confirms that this is appropriate for your exact product.
  • Tell your doctor if you develop side effects or have difficulty following the prescribed schedule.

If you are unsure how to take your medicine, ask your pharmacist before changing your routine.

Azathioprine 75 mg Dosage

There is no single dose that is suitable for everyone. The prescribed amount depends on the condition being treated, body weight, other medicines, blood-test results and how the patient responds.

Your doctor may adjust the dose during treatment to balance its benefits with the risk of side effects. A tablet’s stated strength does not, by itself, establish the correct daily dose.

Missed Dose

If you forget a dose, follow the instructions provided by your doctor or pharmacist. Depending on when you remember, you may need to skip the missed dose and continue with your usual schedule.

Do not take a double dose to make up for a missed tablet. If you have missed several doses or take azathioprine tablet IP 75 mg after an organ transplant, contact your treating team for advice.

Overdose

Taking more azathioprine 75 mg tablet than prescribed can cause serious harm, even if you feel well initially.

Seek urgent medical advice if you have taken too much. Call emergency services if you have severe symptoms or need immediate assistance. Keep the medicine packaging available when seeking help.

Drug Interactions

Azathioprine 75 mg can interact with prescription medicines and other products. Some combinations can increase side effects or change how well a medicine works.

Medicine or medicine group Why it matters
Allopurinol Can substantially increase exposure to it. A specialist must assess the combination and any necessary dose adjustment.
Febuxostat Can increase the risk of serious toxicity and is generally not recommended with azathioprine.
Warfarin Azathioprine may reduce the anticoagulant response, requiring closer monitoring.
Co-trimoxazole May increase the risk of blood-related adverse effects in some patients.
ACE inhibitors May contribute to blood-related problems in certain circumstances.
Other immunosuppressants Combined treatment can increase the risk of infection and other adverse effects.

This table is not a complete list of interactions. Tell your doctor and pharmacist about all medicines, vitamins and supplements you use. Do not start, stop or change a medicine without checking whether it is suitable alongside azathioprine.

Precautions Before and During Treatment

Before starting treatment, tell your doctor about your medical history, allergies, current medicines and any previous problems with azathioprine 75 mg or related medicines. This helps the treating team decide whether the medicine is appropriate and what monitoring is needed.

Blood Tests and Monitoring

Regular blood tests help check blood-cell counts and liver function during treatment. Your doctor may also arrange other tests based on your medical history and the treatment plan.

Keep all scheduled appointments, even if you feel well. Some unwanted changes may not cause noticeable symptoms at first.

Infection

Azathioprine 75 mg can make it harder for your body to fight certain infections. Contact your healthcare professional promptly if you develop a fever, persistent sore throat, chills or other signs of infection.

Tell your doctor if you have been exposed to chickenpox or shingles, especially if you are not sure whether you are immune.

Vaccinations

Speak with your doctor before receiving a vaccination. Some vaccines may be unsuitable during immunosuppressive treatment, and the timing of vaccination may need to be planned around your treatment.

Liver and Kidney Health

Tell your doctor if you have liver or kidney problems. These conditions may affect treatment decisions and the monitoring you need. Report symptoms such as yellowing of the skin or eyes, dark urine or a significant change in how you feel.

Sun Exposure

Long-term treatment with immunosuppressants can increase the risk of certain skin cancers. Protect your skin from excessive sun exposure, use suitable sun protection and tell your doctor about new or changing skin marks.

Pregnancy and Breastfeeding

Tell your doctor if you are pregnant, planning a pregnancy, trying to conceive or breastfeeding. Do not make changes to prescribed treatment without medical advice. Your prescriber can discuss the benefits, risks and monitoring relevant to your situation.

Storage and Disposal

Follow the storage instructions provided with your specific medicine.

  • Keep the tablets in their original packaging where possible.
  • Store the medicine out of the reach of children.
  • Protect it from heat, moisture and light as directed on the packaging.
  • Do not use tablets after the expiry date.
  • Ask a pharmacist how to dispose of unused or expired medicine safely.

Azathioprine 75 mg a Schedule 4 prescription-only medicine in Australia, it requires careful dosing and regular medical monitoring because it affects immune activity and can cause serious side effects. Follow your prescription, attend scheduled blood tests and seek medical advice if you notice unusual symptoms or have questions about other medicines.

If you plan to buy Azathioprine 75 mg, AustraliaRxMeds provides product information to help you understand its uses, possible side effects and precautions. Always follow your prescribing instructions and consult your healthcare professional about treatment decisions.

FAQs

1. What is azathioprine 75 mg used for?

It is an immunosuppressant medicine that reduces the activity of the immune system. Doctors may prescribe it for conditions such as rheumatoid arthritis, certain autoimmune diseases and to help prevent organ rejection after a transplant. The reason for treatment depends on the person's medical condition and treatment plan.

2. What are the bad side effects of azathioprine?

This medication may cause nausea, vomiting, diarrhoea or reduced appetite. More serious problems can include a low blood cell count, liver problems, pancreatitis or severe infections. Contact your doctor if you develop a fever, unusual bruising, persistent abdominal pain or yellowing of the skin or eyes. Seek urgent medical help for difficulty breathing or swelling of the face or throat.

3. Is azathioprine 75 a serious drug?

Azathioprine is a medicine that needs careful monitoring because it can affect blood cell production, liver function and the body's ability to fight infections. It can be helpful for certain conditions when prescribed appropriately, but it is not suitable for everyone. Take it only as directed and attend the blood tests recommended by your healthcare professional.

4. What to avoid while taking azathioprine 75mg?

Do not start new medicines, supplements or herbal products without checking with your doctor or pharmacist. Avoid close contact with people who have contagious infections where possible, and ask your healthcare professional before receiving a vaccine, particularly a live vaccine. Limit excessive sun exposure and use sun protection. Do not stop treatment or change your dose without medical advice.

5. Can 75 mg of azathioprine increase the risk of infections?

Yes. It reduces immune system activity, which can make infections more likely or harder for the body to fight. Contact your doctor promptly if you develop a fever, chills, a persistent sore throat or other signs of infection. Do not ignore symptoms simply because they seem mild.

6. Can you stop taking azathioprine suddenly?

Do not stop taking it without discussing it with your doctor. Stopping treatment may allow the condition being treated to become active again or increase the risk of problems after an organ transplant. If you are experiencing side effects or think the medicine is not helping, seek medical advice before making changes.

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    Imjame Sliquian –

    Nothing over the top to say, just a decent experience and no major issues.
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About the Doctor

Dr. Arjun Srivastav

Medical Reviewer (Pharm D)

✔ Medically Reviewed • Updated: 10/16/2026

Education: Graduate Diploma in Clinical Practice - University of Sydney,

Clinical Pharmacist (Pharm D) Doctor of Medicine (MD) – University of Melbourne Biomedical Engineering – Monash University Graduate Diploma in Clinical Practice - University of Sydney, Arjun Srivastav is a dedicated Clinical Pharmacologist and the E-commerce Operations Manager at AustraliaRxMeds. With a Doctor of Pharmacy (Pharm D) and over 10 years of clinical experience at prestigious institutions like Wockhardt and Apollo Hospitals, Arjun specializes in drug safety, digital healthcare accessibility,...

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