Diloxanide Furoate 500 mg

What Is Diloxanide Furoate 500 Mg?

Diloxanide Furoate 500 mg is an antiparasitic medication primarily used to treat intestinal infections caused by the parasite Entamoeba histolytica, which causes amoebiasis.

It is known as a luminal amoebicide, meaning it works within the intestines to eliminate amoebic cysts and parasites that remain in the bowel.

• Asymptomatic Amoebiasis, which means they actively carry the Parasitic Infection without any major symptoms.
• Intestinal Amoebiasis, that is, people who suffer from amoebic dysentery or amoebic liver abscess.

It is the generic element inside the medicine, which belongs to the luminal amebicide group of medicines. Sometimes doctors can combine Diloxanide with other medicines like Metronidazole or Tinidazole.

Who Manufactures Diloxanide Furoate 500 Mg?

Franco-Indian Pharmaceuticals

Composition And Appearance Of Diloxanide Furoate:

✓ Active Ingredient:

Diloxanide Furoate is the chief generic substance, with each pill having a dose of 500 mg.

✓ Appearance:

In its purest generic form, Diloxanide Furoate will appear as a white powdery substance only.

Individual branded medicines come in different shapes, sizes, and colours.

Pharmokinetic Action And Lasting Time Of Diloxanide Furoate

✓ Initial action:

Within 30 minutes to an hour, the medicine begins absorption and initial action.

✓ Peak levels:

When you take the medication, it gets into your bloodstream quickly. The medication reaches its level in your blood within 2 hours.

✓ Total duration:

A single medicine lasts in your body,y showing its effects for up to 6 hours.

✓ Relief from symptoms:

You can find that your symptoms slowly start to reduce within a day or two of taking your pills on time.

How Diloxanide Furoate 500 Mg Works?

• Diloxanide Furoate acts directly in the intestinal lumen, where it destroys amoebic parasites and cysts.
• This helps clear the infection and reduces the risk of spreading the parasite to others.
• Diloxanide Furoate works locally inside the gut rather than being activated in the bloodstream, which is why it is called a luminal amebicide.
• It targets the trophozoites, which are the multiplying amoeba in the guts.
• It blocks several vital metabolic functions of the amoeba by inhibiting the production of certain proteins needed for glucose processing.
• Without being able to take glucose and convert it into energy, the amoeba essentially dies.

What Is The Dosage Of Diloxanide Furoate 500 Mg

Standard adult dose:

Doctors recommend a dose of Diloxanide Furoate 500 mg to be taken 3 times per day for up to 10 days.

Dose in children:

✓ Above 25 kg: Dose of 25 mg per kg of bodyweight is given in three different doses during the day for 10 days.

✓ Under 25 kg: If your child is lower than 25 kg in weight, the drug is not safe for them.

With or without food:

Doctors recommend that you always use Diloxanide Furoate for yourself or your child only after a meal.

It is because this helps to generate a protective layer inside the stomach and avoids having side effects like nausea and flatulence.

Method of use:

Take it with water and avoid crushing or breaking the medicine in half when taking it.

Time intervals:

Since you need to take three pills a day, it is better to keep a time gap of at least 8 hours between consecutive doses. Thus, you can take the medicines once each during the early morning, during the afternoon and once at night.

Best Benefits Of Taking Diloxanide Furoate 500 Mg

✓ Kills both active and dormant cysts of amoeba:

Diloxanide Furoate 500 mg is a medication which works bn actively multiplying trophozoite amoeba and even the ones which are dormant in the body. This helps you to get a complete remedy and avoid any chances of recurring infection.

✓ Highly targeted action:

The medicine works locally in the intestines rather than being present in the bloodstream. This ensures a more direct action on the amoeba at the site of the infection.

✓ Rapid relief from symptoms:

Even though for a complete remedy you may need to take the medicine for 10 days, you can get relief from symptoms within 1 to 2 days of using the medicine on time.

✓ Low risks of side effects

Since the medicine is activated and works only inside the intestines rather than being present in the bloodstream, there are little chances of having systemic side effects like drowsiness, toxicity and so on.

✓ Effective in the treatment of asymptomatic patients:

The medicine works equally well in those patients who are carriers of the amoeba but do not actively show any signs of the infection.

What are the medicines that interact with Diloxanide?

✓ Blood Thinners:

Using medicines like Warfarin can increase the chances of having bruises or internal bleeding.

✓ Phenytoin, Carbamazepine:

High levels of Phenytoin can become toxic when combined with Diloxanide. This drug interaction can usually lead to side effects like tremors, confusion, loss of coordination or tremors.

✓ Acid-reducing medicines like Cimetidine:

Combining the effects of Diloxanide Furoate 500 mg with acid-reducing medicines like Cimetidine can potentially prolong the time for which the former lasts in your body, increasing the chances of drug toxicity.

✓ Medications Affecting Blood Counts:

Clozapine or certain NSAIDs can affect your CBC count and cause other health problems.

Side Effects of Diloxanide Furoate 500 mg

Common Side Effects

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Nausea, vomiting, stomach pain

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Occurs usually when you take the medicine in an empty stomach.

Diarrhea

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Consult with a doctor if it continues for more than a few days.

Metallic taste in the mouth

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Take water to get rid of it.

Dizziness, headache

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usually less reported but you should take rest and see if it

Mild itching and rashes

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Could be sign of an allergic tendency, so consult with a doctor right away.

What Precautions And Warnings Should You Know About Diloxanide Furoate?

✓ Warning with alcohol:

Taking alcohol may cause a few mild issues like stomach cramps, indigestion, bloating and so on.

✓ Blood Count Monitoring:

Remember that doctors may frequently conduct blood tests and CBC count during the course of this medicine.

When Not To Use Diloxanide 500 Mg?

✓ Having an allergic tendency:

Do not take Diloxanide Furoate if you are allergic to Diloxanide, the generic element of the medicine or else you can get allergic reactions like-

• Allergic reactions on the skin
• Swelling in your face or throat
• Trouble breathing

✓ Liver Disease:

The liver is very important because it breaks down this medicine. If your liver is not working, well, the medicine can build up,p leading to drug toxicity. Having severe liver disorders, it is completely unsafe to take Diloxanide.

✓ Kidney Issues:

If your kidneys are not working well as they, you should need to take a smaller amount of the medicine. With critical kidney issues like kidney failure, the doctors will not recommend this pill.

✓ Pregnancy and Breastfeeding:

You should not take this when you are pregnant during the first few months. This is because the doctors do not know what it can do to the baby. This medicine can get into your breast milk. You need to talk to a doctor to figure out if it is safe for your baby.

✓ Existing Blood Disorders:

Avoid the medicine if you have a medical history of-

• Low WBC count
• Bone marrow suppression
• Severe anaemia
• Low platelet count

Where To Store And Disposal Guidelines Of Diloxanide 500 Mg?

✓ Storage

• Store Diloxanide 500 mg tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F).
• Keep the medication in its original packaging until use.
• Protect it from excessive heat, moisture, and direct sunlight.
• Do not store it in bathrooms or other damp places.
• Keep the medicine out of the reach of children and pets.
• Check the expiration date regularly and do not use expired tablets.

✓ Disposal

• Do not flush Diloxanide 500 mg tablets down the toilet or pour them into drains unless specifically instructed by a pharmacist.
• If the medicine has expired or is no longer needed, dispose of it through a local medicine take-back program if available.
• If no take-back program is available, mix the tablets (without crushing them) with an undesirable substance such as used coffee grounds or cat litter, place the mixture in a sealed plastic bag, and dispose of it in household trash.

Where To Buy Diloxanide Furoate 500 Mg In Australia?

You can rely on trusted platforms such as australiarxmeds.com for secure and discreet delivery across Australia.

Diloxanide Furoate 500 is available for online purchase through pharmacy websites, but it’s important to choose reputable and licensed sellers to guarantee product quality, authenticity, and safety.