Seroflo Inhaler 50 Mcg

Last Updated on 04/14/2026 ✔ Medically Reviewed by Dr. Arjun Srivastav

What is Seroflo Inhaler 50 Mcg?

Seroflo Inhaler 50 is a combination inhaler used to manage asthma and chronic obstructive pulmonary disease (COPD) by improving breathing and reducing inflammation.

When you are dealing with respiratory problems, Seroflo Inhaler 50 Mcg can be a lifesaver. People with Asthma and chronic obstructive pulmonary disease (COPD) can benefit from the combination of two essential medications, fluticasone and salmeterol, which is a combination of these medications.

✓ Composition

• Salmeterol – Relaxes airway muscles
• Fluticasone – Reduces airway inflammation

👉 Dual-action formula for better control of respiratory symptoms

✓ Manufacturing

Cipla Limited

How to work the Seroflo 50 Inhaler? 

Step-by-Step Working Mechanism

✓ 1. Airway Relaxation (Bronchodilation)

• Salmeterol relaxes the muscles around the airways
• This opens up the air passages in the lungs

👉 Result: Easier airflow and reduced breathlessness

✓ 2. Reduces Inflammation

• Fluticasone decreases swelling and irritation in the airways
• Prevents mucus buildup and narrowing

👉 Result: Less wheezing and irritation

✓ 3. Long-Term Control

Works over time to:

• Prevent asthma attacks
• Improve lung function
• Reduce the frequency of symptoms

👉 It is a maintenance inhaler, not for instant relief

What are the key uses of the Seroflo 50 Inhaler? 

✓ Asthma Management

• Controls chronic asthma symptoms
• Reduces wheezing, coughing, and breathlessness
• Helps prevent asthma attacks

✓ Prevention of Asthma Attacks

• Used daily to reduce the frequency and severity of attacks
• Keeps the airways open and less inflamed

✓ Chronic Obstructive Pulmonary Disease (COPD)

• Helps manage COPD symptoms
• Improves airflow and breathing comfort
• Reduces flare-ups

✓ Long-Term Breathing Control

Maintains stable lung function

Reduces dependence on rescue inhalers

Dosage

✓ Standard Dosage (General Guide)

1 inhalation twice daily (morning & evening)
👉 This is the most commonly prescribed dose

✓ Duration of Use

• Used for long-term maintenance
• Continue even if symptoms improve (unless doctor advises otherwise)

Special Considerations

✓ Adults

• Usually 1 puff twice daily
• Dose may vary depending on severity

✓ Children

• Use only if prescribed
• Dose adjusted based on age and condition

✓ Important Instructions

• Do not exceed the prescribed dose
• Do not use for sudden asthma attacks
• Do not stop suddenly without consulting a doctor

How to Take Seroflo Inhaler 50 Mcg

Step-by-Step Instructions

1. Prepare the Inhaler

• Remove the cap
• Shake the inhaler well (5–10 seconds)

2. Breathe Out Fully

• Exhale completely away from the inhaler

3. Inhale the Medicine

• Place the mouthpiece between your lips
• Press the inhaler once while slowly breathing in deeply

4. Hold Your Breath

• Hold for 5–10 seconds
  Helps medicine reach deep into the lungs

5. Repeat if Needed

• Wait about 30–60 seconds before the next puff

6. Rinse Your Mouth

• Gargle and spit out water after use

Prevents oral thrush (fungal infection)

Side Effects

✓ Common Side Effects

• Throat irritation
• Hoarseness (voice change)
• Cough
• Headache
• Dry mouth

✓ Fungal Infection (Oral Thrush)

• White patches in the mouth or tongue
• Soreness in the mouth

👉 Caused by Fluticasone (steroid component)
✔ Prevent by rinsing the mouth after use

✓ Less Common Side Effects

• Muscle cramps
• Tremors (shaking hands)
• Palpitations (fast heartbeat)
• Nervousness

👉 Usually due to Salmeterol

✓ Serious (Rare) Side Effects

• Severe allergic reaction (rash, swelling, breathing difficulty)
• Worsening breathing (paradoxical bronchospasm)
• Chest pain or irregular heartbeat

👉 Seek immediate medical help if these occur

Safety Features 

• Built-in Dose Tracking: The counter section easily allows you to track your dose and know when your inhaler is empty. 

• Anti-inflammatory Guard: Fluticasone, which is the generic compound inside the medication, also helps avoid inflammation.  

• CFC-Free Propellant: The propellant inside the inhaler, HFA-134a, does not harm the environment once you dispose of it.  
• Spacer Compatibility: You can use the inhaler with a spacer, like a Zerostat or Zerostat VT, if you have trouble breathing in the medicine from the inhaler at the time. 

Important Maintenance Tip 

✓ Dry clean every week:

The important thing to remember about the Seroflo MDI is to keep it dry. You should not take the metal canister out of the part to clean it, which is different from some other inhalers. 

• You need to clean the Seroflo MDI every week to stop the medicine from building up and blocking the spray. 

• Use a dry cloth or tissue to wipe the inside and outside of the mouthpiece and the plastic part. 

• Do not get the metal canister wet. Water can affect the medicine and the way it sprays. 

✓ Storing the Seroflo MDI Properly:

• Keep the Seroflo MDI in a place at room temperature. The ideal temperature threshold is between 2 °C and 25 degrees Celsius.  

• Do not store the Seroflo MDI in the bathroom or near a sink. The heat and dampness can damage the medicine. 

• Always put the cover back on the mouthpiece after you use the Seroflo MDI. This will stop dust and other things from getting into the device. 

Essential Precautions 

✓ Avoid using it as a rescue inhaler:

Do not use Seroflo as a rescue inhaler. You should never use Seroflo to treat serious asthma attacks or status asthmaticus. Always carry an asthma rescue inhaler like salbutamol with you for emergencies. 

✓ Disclosure of medical history and medical checkup:

You have to tell your doctor about health problems. If you have health problems, you need to inform your doctor because they may need to monitor you more closely or change the dose of Seroflo. 

• If you have diabetes, you need to tell your doctor because Seroflo can increase your blood sugar levels. 

• If you have heart problems, you need to tell your doctor because Seroflo can cause your heart to beat faster or cause palpitations or high blood pressure. 

• If you have potassium levels, you need to tell your doctor because Seroflo can lower your blood potassium levels even more. 

• If you are worried about your bone health, you need to tell your doctor because using Seroflo for a time can decrease your bone mineral density and cause osteoporosis. 

• If you have eye problems, cataracts, and glaucoma,  matters can get worse using the inhaler for a long time. 

Important safety advice 

Drug Interactions:

You should tell your doctor about all the medicines you are taking. This includes things like: 

• Beta-blockers, such as atenolol or propranolol 

• Antivirals, such as ketoconazole or ritonavir 

• Diuretics, or water tablets 

✓ Pregnancy:

Seroflo inhaler is safe during pregnancy to keep asthma symptoms away. However, the doctors will add further safety and caution tips to avoid any complications. 

✓ Breastfeeding:

Breastfeeding mothers will have to avoid use of the inhaler for more than a few weeks.

Studies from the TGA show that long-term use can cause the drug to be present in your breastmilk, which is deadly for your infant.  

✓ Age guidance use:

This medicine is not usually given to children under 4 years old. Some types of this medicine are for kids who are 12 years old or older.

If your child is taking this medicine for a long time, the doctor should keep an eye on how they are growing. 

Precautions of Seroflo Inhaler 50 Mcg

When using Seroflo Inhaler 50 Mcg, your safety is of the utmost importance. Here are some precautions to take:

1. If you are thinking about using Seroflo Inhaler 50 mcg, you should talk to your doctor before starting or changing any medications.
2. They will help you determine if Seroflo is right for you.
3. You should report any allergies you have to your doctor, especially if you are allergic to Fluticasone or Salmeterol. It is important to inform your doctor about these sensitivities to ensure your safety.
4. If you are pregnant, expecting to become pregnant, or nursing, you should consider the risks and benefits of using these products with your doctor.
5. Drugs: Make sure your doctor is aware of all drugs you’re taking, including over-the-counter meds and vitamins. Some medications may interact with Seroflo and cause adverse reactions.