Liofen 25 Mg (Baclofen)

Last Updated on 05/04/2026 ✔ Medically Reviewed by Dr. Arjun Srivastav

What Is Liofen 25 Mg?

Liofen 25 mg contains baclofen, a muscle relaxant used to relieve muscle stiffness, spasms, and pain.

Liofen 25 mg is a medicine that helps relax muscles. It is used to treat muscle stiffness and tension.

Doctors prescribe Liofen 25 mg for problems like sclerosis. It also helps with palsy and injuries to the brain and spinal cord. The muscle relaxant effect of Liofen 25 mg helps reduce muscle tension.

Manufacturer:

• Sun Pharmaceutical Industries Ltd is the manufacturer of the brand-name Liofen and all its doses.

Composition And Appearance:

✓ Active Ingredient:

The chief generic element inside the medicine is Baclofen, with a dose of 25 mg.

✓ Inactive Ingredients Or Excipients:

The tablets have some extra ingredients that are not usually listed on the packaging. These help make the tablet easier to swallow and protect the ingredient.

✓ Appearance:

The pills come in a sachet with 10 pills in each strip. These pills are usually small, round, and white or a bit off-white.

Onset Of Action:

✓ Initial Relief:

You can start to feel better within one to three hours after you take the tablet.

✓ Peak Effectiveness:

The medicine gets to its point in your blood around two to three hours after you take it.

✓ Full Benefit from The Treatment:

When you take the medicine, it starts working fast, but you will not feel the full effect of the treatment, like your muscles being a lot less stiff and having fewer spasms for a few days, ays usually 3 to 4 days or even a few weeks.

This is because your doctor needs to find the dose for you, and that takes some time.

✓ How Long Does It Last:

The medicine usually keeps working in your body for around 7 to 12 hours after you take one dose of the treatment.

Uses of Liofen 25 mg

Liofen 25 mg (baclofen) is mainly used to relieve muscle stiffness, spasms, and pain caused by nerve-related conditions.

✓ Muscle Spasms & Spasticity

• Reduces tight, stiff muscles
• Improves movement and flexibility

✓ Neurological Disorders

Used in conditions like:

• Multiple Sclerosis
• Cerebral Palsy
  👉 Helps control involuntary muscle contractions

✓ Spinal Cord Injuries

• Relieves muscle spasms caused by nerve damage
• Improves comfort and mobility

✓ Chronic Pain Related to Muscle Tightness

• Helps reduce pain due to muscle tension and stiffness

How Liofen 25 Mg Works?

✓ Stimulating GABA receptors:

Baclofen helps the body by acting like Ggamma-aminobutyricacid, which is a very important chemical that helps our body relax. It does this by working with the GABA receptors in our body, the GABA-B receptors.

✓ Blocking nerve signals:

When Baclofen works with these GABA-B receptors, it stops the nerve endings from sending many signals.

This means that our muscles do not get many messages, which helps our muscles relax and not get too tense. Baclofen is good at blocking these nerve signals, which is very helpful.

✓ Blocking Spinal Reflexes:

It works at the spinal cord to stop the reflexes that cause sudden muscle contractions or spasms.

✓ Calming Nerve Cells:

It helps open up potassium channels and reduces calcium in nerve cells. This makes nerve cells less active, which calms the system and allows muscles to move more smoothly.

Dosage of Liofen 25mg:

✓ Initial Titration:

Take 5mg thrice daily for 3 days.

✓ Maintenance dose:

Take 30-75mg daily, divided into several doses for the days referred by your doctor.

✓ Maximum Dose:

Daily dose must not be more than 100 mg.

Benefits Of Liofen 25 Mg:

Therapeutic Benefits

✓ Reduction of muscle spasticity:

It helps to relax muscles that are too stiff. This stiffness is often caused by conditions like sclerosis, cerebral palsy, and spinal cord injuries.

✓ Less muscle spasm frequency:

It also helps to reduce the number of muscle spasms. These spasms happen when your muscles contract suddenly, and you have no control over them. It works on the cord to make these spasms less frequent and severe.

✓ Gaining back muscle strength:

Liofen helps keep your muscles strong. It does this by reducing stiffness without making your muscles weak.

✓ Gets rid of pain:

Liofen also helps with the pain that comes with muscles. It calms down the muscles that are contracted. This helps stop the cramps and discomfort that you can get when your muscles are too tense.

Daily Life Benefits

✓ Enhanced Mobility:

When the muscles are not as tight, the limbs can move easily. This makes walking and moving around a lot smoother. Enhanced Mobility is important for people who have trouble getting around.

✓ Supports Physical Therapy:

This thing can make exercises that people do in therapy work better. It can also make these exercises hurt less.

This means that people can reach their recovery goals faster.

✓ Improved Quality of Life:

When people have muscle spasms, they can do everyday things with more comfort. They can also do things on their own without needing help.

It makes a difference in their daily lives and helps them feel better about themselves.

Drug Interactions:

✓ Opioids:

Taking Liofen with painkillers like Morphine, Codeine, or Oxycodone can make you extremely sleepy. Even stop you from breathing, which can be fatal.

✓ Benzodiazepines:

If you take Liofen with anxiety or sleep medicines, like Alprazolam or Diazepam, it can make you too sleepy and even put you into a coma.

✓ Antidepressants:

Some medicines like Amitriptyline or Lithium can cause problems like forgetting things or feeling more confused.

✓ Blood Pressure Medications:

Liofen can make your blood pressure go down. If you take it with blood pressure medicines, like Amlodipine or Diltiazem, em you might feel dizzy or faint.

✓ Anti-Parkinson’s Agents:

Taking Liofen with Levodopa or Carbidopa can make you more confused or see things that are not there.

✓ Antihistamines: Medicines:

Pills like Diphenhydramine or Benadryl and Cetirizine or Zyrtec can make you feel sleepy.

✓ Cough Suppressants:

If you take products that have Dextromethorphan in them, it can make the sedative properties of Liofen stronger.

✓ NSAIDs:

Usually, people think these are safe. Some places, like the NH, S  say you should tell your doctor if you are taking Ibuprofen because it might change how your kidneys handle Baclofen.

Precautions And Warnings:

With Existing Health Conditions:

Tell the doctors if you have health issues like-

• Kidney disease
• Epilepsy
• Stomach ulcers
• Depression or mania disorder
• Schizoprenia

General Warnings:

✓ Avoid driving, operating heavy machinery, or using sharp objects:

Dizziness and coordination problems are possible with Liofen. This medicine can make your vision blurry or make you feel sleepy. You should not drive a car. Use big machines until you know how Liofen affects you.

✓ Stay away from alcohol use:

You should not drink alcohol when you are taking Liofen. Alcohol makes the sleepy effects of Liofen much stronger, which can cause you to breathe slowly, and this can be very dangerous.

✓ Never stop taking suddenly:

If you stop taking this medication all of a sudden, you can get bad withdrawal symptoms, including hallucinations and delusions, high body temperature or mild fever,r and seizures.

✓ Geriatric use:

The drug can be bad for older people because it makes them feel sleepy. This can cause them to get confused, see things that are not there, and fall.

✓ Pregnancy:

You should only take Liofen when you really need to, and your doctor says it is okay. This is because the drug can get to the baby and make it sick after it is born.

✓ Breastfeeding:

Liofen can get into the milk that you feed your baby. You need to talk to your doctor about whether the good things about taking Liofen are more important than the bad things that might happen to your baby.

When Not To Use:

✓ Have an allergy to Baclofen:

You are allergic to Baclofen or some other things that are in the Baclofen tablet.

✓ Have stomach ulcers:

You have had stomach ulcers before, or you have them now. These ulcers are in your stomach, and they are called peptic ulcers.

✓ Need Muscle Tone for Balance:

We have to be in a state where our muscles are right so we can move safely or stay balanced.

✓ Using This with Kids:

Do not give this to children who weigh less than 33 kg or are younger than 12 years because it has not been proven to be safe and work well for children of this age.

Storage And Disposal:

✓ Storage:

Store the sachet of Liofen 25 mg pills in a room where there is no direct sunlight. The room should not have a temperature more than 30 degrees Celsius or have high humidity.

✓ Disposal:

Always discard empty sachets or out-of-date expired medicines safely in a disposal bag.

Where To Buy Liofen 25 Mg In Australia?

To buy Liofen 25 mg in Australia, you can check out online pharmacy AustraliaRXMeds. We have Liofen 25 mg available on a prescription basis, along with many other medicines, as variants for relieving muscle pain and rigidity.