Dr. Arjun Srivastav What is Itraconazole 130 mg Tablet?
Itraconazole 130 mg is a generic element, which is given to treat different fungal and yeast infections in humans. The doctors recommend the medicine for conditions like-
- Candidiasis which affects the skin and vagina
- Oral thrush
- Esophageal infections
- Meningitis
The doctors first assess the type and severity of the infection before recommending a suitable dose. Use the tablet, maintaining the dose given by the doctors along with the list of cautions and safety tips.
Follow the timing for use and inform the doctors about any other gastric and dental infections first. Do not use any other anti-parasitic medicine at the time of regularly taking the Itraconazole 130 mg.
Manufacturer
Intas Pharmaceuticals Ltd is one of the largest manufacturers of the generic ingredient Itraconazole tablet in India.
Other branded manufacturers: Some of the largest branded drug manufacturers are-
- Glenmark Pharmaceuticals
- Cipla Ltd
- Mankind Pharma
- Sun Pharma
- Abbott
Composition
- Active ingredient: Itraconazole itself is the chief generic element.
- Appearance: In its purest API form, Itraconazole looks like a white crystalline powder, which looks white or slightly yellowish in colour.
Onset of Action
- Beginning of action: The action of the medicine usually peaks within 1 hour of taking the medicine.
- Peak action time: Itraconazole 130mg usually gives a peak action time of 3 to 4 hours.
- Complete removal: For the entire action of the drug to be completely removed from your body, it may take about 5 to 7 hours.
How does Itraconazole 130 mg work?
Stops muscle movement of Parasite: Studies show that the action of Itraconazole 130mg tablet stops the action of certain chemicals and proteins, which are needed for muscle movement by the parasites, and works in your body.
Paralyse the parasite: Due to the absence of such proteins and chemicals, the parasites eventually are not able to move, grow, and reproduce.
In simple words, they will be paralysed as a result of which they eventually die within a couple of days, leaving you to recover from the infection.
Dosage of Itraconazole 130 mg
For adults: The doctors for mild to moderate variants of fungal infection generally give the 130 mg dose. Usually, for treating oral infections and meningitis, the doctors recommend a dose of Itraconazole 130 mg, depending on the severity of the condition.
For skin infections, usually a smaller dose, like 130 mg, is enough. There are other higher doses available, like-
Available dose, like Itraconazole 130 mg tablet
| Medicines | Tablet | Price | Price/Unit | Buy Now |
|---|---|---|---|---|
| Itraconazole 50 Mg | 90 Capsule/s | AUD $156.62 | (1.74 / Unit) | Buy Now |
| Itraconazole 100 Mg | 200 Capsule/s | AUD $269.34 | (1.34 / Unit) | Buy Now |
| Itraconazole 200 Mg | 200 Capsule/s | AUD $315.24 | (1.57 / Unit) | Buy Now |
For children, the doctors check the age and weight of the child, based on which a suitable dose is given. However, in any case, the dose is generally given below 130 mg.
Suitable forms of administration
For adults: The doctors recommend the oral tablet to treat infections affecting the oesophagus and meningitis.
For children: Generally, the doctors recommend the syrup version for use in children below the age of 6years.
Overdose
Never try to increase the strength or dosage of Itraconazole 130mg antibiotic in hopes of a faster relief, as it can cause many side effects.
Missed dose
Frequently missing your dose on time may not help relieve the infection at all.
Clinical Benefits of Itraconazole 130mg for Fungal Infections
Reduction of symptoms: It helps to get rid of the infection and relieve the symptoms as well. The patient starts to notice a reduction of symptoms within 3 to 4 days of using the medicine.
Faster treatment: You usually get well within 2 to 3 weeks of using the medicine daily. For mild infections, recovery is possible within a week.
Drug Interactions
Other oral pills or creams with the same composition: Using other pills or creams for vagina infections or candidiasis when already taking Itraconazole 130 mg pills leads to severe overdose and drug toxicity.
antifungal agents: Itraconazole is not safe with other antifungal generic medications like Miconazole, Fluconazole, again causing drug toxicity and several side effects.
Some types of antibiotics, like Amoxicillin: Studies show that some types of antibiotic medicines like Amoxicillin can also interact with Itraconazole, reducing its effects.
What are the Side Effects of Itraconazole 130mg?
Common Effects
Headache, Dizziness: Sit or lie down and take rest to see if the conditions improve, as such side effects last only a few minutes.
Fatigue: It is best to take the injection after your daily work hours.
Flushing: A feeling of warmth on the face, palms, and neck area, which needs to be reported to the doctors if it lasts for more than a few days.
Drowsiness: Avoid driving a car or taking alcohol, as it can increase drowsiness.
Muscle cramps: Visit a doctor if the issues continue for more than a few days.
Intense Effects
Diarrhoea with blood: Visit your doctor for checkups.
Severe stomach pain: having severe muscle cramps, feeling full, or bloating will need doctor treatment.
Mild fever that persists: if you have a mild, persisting fever, stop using the medicine and contact your doctor.
Blur vision: Avoid driving or operating heavy machinery, as there is a risk of injury.
✅ Safety Advice
- Only with a prescription from a doctor.
- For confirmed fungal infections.
- When prescribed correctly and for the right amount of time.
👉 Self-medication can increase the risk of side effects and drug interactions.
Precautions & Warnings
Addictions: Use of any addictions in the end is going to make the action of the Itraconazole 130mg less effective. Studies show that it may also increase the chances of many side effects.
Driving: Even though no major interaction has been found, do not drive if you get a headache or feel dizzy or restless after taking the pill.
Use with existing health disorders: Use of the Itraconazole 130mg may not be safe if the patient has certain other health issues, like-
- Kidney infections
- Liver disorders
- Low hormonal levels
- Heart problems
- Severe diabetes
When not to use?
Pregnancy: Studies show that although no major interaction was found, use of a high dose might not be safe. Neither is it safe to use the medicine for a longer tenure in such cases.
Breastfeeding: In 2018, the WHO scientists found that traces of Itraconazole 130 mg were found in the breastmilk of mothers after studying it.
Thus, use of the dose may not be safe if you have an infant who is very dependent on your milk. Tell the doctors about it in advance.
Signs of allergic tendency: People who are allergic to using Itraconazole 130 mg capsules must avoid using a small dose. Tell the doctors if you have used any brand of Itraconazole 130mg before and ended up with-
- Severe skin inflammation
- Swelling of limbs
- Fever
- Vomiting
- Nausea
In case of any severe side effect: Those who suffer from any major side effect as given above must stop the course immediately. It includes blurred vision, diarrhoea with blood, persistent fever, and bloody diarrhoea.
Storage and Disposal
Store the Itraconazole 130 mg pills not in the fridge at too low temperatures. The normal room temperature with less humidity is a much better option. Dispose of the empty sachet of medicine safely to avoid any kind of environmental contamination.
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FAQs
Can Itraconazole 130 mg be given to my child?
Use of the Itraconazole 130mg needs verification if it is given to a baby whose age is below 2 years. Doctors usually recommend a smaller variant based on the age and weight of the children.
Is it safe to use Itraconazole 130mg daily?
Yes, as per studies at the TGA, and WHO, use of the Itraconazole 130mg is necessary for daily use to get rid of the infection in a few weeks or days.
Is it safe to use other antiallergics with Itraconazole 130mg?
In case your body suffers from any other allergy or infection, tell it to the doctors. Studies done at the EMA show that some allergic medicines that reduce histamine levels may cause drug interactions and, in this case, crop up allergic issues and make it more severe.
Will the doctors tell me to have some changes in my diet too?
Yes, because of teeth or gastric infections caused by parasites, your body’s digestive and absorption system may not be working well. As a result, you need to focus on food items that can be digested easily. The doctors say that you need to take plenty of water, soups, rice, simple bread, and avoid complex carbs and fats that are contained in most junk food items.
