HQ Star 400 Mg

Last Updated on 05/29/2026 ✔ Medically Reviewed by Dr. Arjun Srivastav

What Is HQ Star 400 Mg?

HQ Star 400 is a prescription medicine containing Hydroxychloroquine 400 mg, used to treat autoimmune diseases and malaria.

It helps control inflammation and regulates the immune system when it becomes overactive.

HQ Star 400 is a medicine that contains Hydroxychloroquine 400 mg. It is commonly used to treat and manage autoimmune conditions and certain parasitic infections.

The medicine HQ Star 400 mg is something that doctors prescribe to treat diseases where the body’s immune system is not working correctly.

HQ Star 400 mg is also used to treat some types of infections that are caused by parasites.

The main ingredient in HQ Star 400 mg is Hydroxychloroquine, and each dose of HQ Star 400 mg has 400 mg of Hydroxychloroquine in it.

Manufacturer:

Leeford Pharma Pvt Ltd

Composition And Appearance

✓ Active Ingredient:

Each tablet has 400 milligrams of Hydroxychloroquine Sulphate, as per the Indian Pharmacopoeia.

✓ Excipients:

They are substances that do not have much effect when they are alone. They are used as substances that bind, fill, and coat other substances. The substances that are frequently used in these tablets are Maize starch, Lactose, Magnesium stearate, and Hypromellose, which acts as the film coating of the tablets; Hypromellose is the one that acts as the film coating.

✓ Appearance:

It is a solid, film-coated tablet which is oval-shaped and of a white/off-white colour.

Onset Of Action:

✓ For Autoimmune Conditions

If you are taking it for arthritis or lupus, you will not feel the effects away.

• When you first start taking it usually takes 4 to 12 weeks of taking it every day before you notice that your joint pain, swelling, or skin rashes are getting better.
• The best results often take 6 months to happen.
• That is because the medication needs to build up in your blood and tissues to really work on your system and make it respond better to arthritis or lupus treatment with this medication.

✓ For Malaria

Treatment:

This medicine starts working when used to treat malaria. It begins to attack the parasites in the blood within hours.

It still takes some days for symptoms, like fever, to go away completely.

Prevention:

To prevent malaria, it takes some time for the medicine to build up and protect you.

So, doctors usually say to start taking it 1 to 2 weeks before you travel to an area where malaria is common. For Diabetes (Glycaemic Control)

Timeline:

As is also seen in autoimmune diseases, there will be a gradual effect on the patient’s blood sugar (as reflected in the HbA1c test results).

The significant improvement may be seen after 3-6 months of regular use of the medication.

How Does HQ Star 400 Mg Work?

✓ In Autoimmune Diseases:

Where there is an autoimmune disorder like Rheumatoid Arthritis or Lupus, your immune system will attack your own tissues. HQ Star “turns down” this response in the following ways:

✓ pH Adjustment:

It interferes with the process of lysosomal activity (lysosomes function as the cell’s waste disposal units) and raises their pH.

This prevents the cell from “presenting” self-antigens, which is what prompts the immune system to attack the joints or the skin.

✓ Cytokine Reduction:

Reducing signalling pathways reduces cytokine production, which helps ease inflammation and swelling.

✓ Protection from Ultraviolet Light (for Lupus cases):

Here, it helps control skin reactions to sunlight.

✓ In Malaria:

HQ Star inhibits the change of plasmodium into hemozoin, a non-toxic substance for the parasite. This stops the parasite from attacking the RBCs in the blood.

Dosage Of HQ Star 400 Mg:

Rheumatoid Arthritis

✓ Starting Dose:

A pill of 400 mg to 600 mg each day. This may be given once daily or twice a day.

✓ Maintenance Dose:

After a few days, the doctors feel the maintenance dose is reduced to half, about 200to 300 mg per day.

✓ Safety Limit:

The dose must not be more than 5 mg/kg body weight.

✓ Systemic Lupus Erythematosus (SLE):

200 mg to 400 mg dose each day.

Malaria

✓ Prevention (Prophylaxis): 400 mg once a week.

✓ Dose Schedule:

Begin 1 or 2 weeks before travel to a malaria-infected region, while in that region continue once-weekly dosage, and after leaving the region continue for 4 weeks every week.

Benefits Of HQ Star 400 Mg:

For Rheumatoid Arthritis (RA)

✓ Disease Modification:

Along with reducing pain, it reduces the damage to joints.

✓ Inflammation Reduction:

Here, it treats signs of morning stiffness, swelling, and tenderness in the joints.

For Lupus (Sle)

✓ Life extension:

Several studies suggest that regular consumption of Hydroxychloroquine prolongs the life span of individuals affected by Lupus.

✓ Prevention of flares:

It serves as the “gold standard” medication to lower the incidence of flares in the case of Lupus.

✓ Skin and hair protection:

This medication effectively clears discoid lupus rash and prevents hair loss related to the condition.

✓ Protective effect on organs:

It reduces the harm to critical organs like the kidneys and the brain from autoimmunity.

Drug Interactions:

✓ Anti-arrhythmic:

Drugs such as Amiodarone or Sotalol can cause severe side effects.

✓ Specific Antibiotics:

Azithromycin, Clarithromycin, and Erythromycin cause a risk of heart rhythm issues.

✓ Antipsychotics Haloperidol or Quetiapine:

Can cause a chance of a heart attack.

✓ Metformin or Sulfonylureas:

Glimepiride may result in Hypoglycemia.

✓ Digoxin:

HQ Star may cause an increased concentration of Digoxin in your system

Precautions And Warnings:

Vision & Eye Health

✓ Eye Checkups:

Should you be taking this drug for several months, you must undergo an initial eye examination along with follow-up appointments annually.

✓ Red Flags:

See your physician immediately should you experience “blind spots,” trouble reading, blurred vision, or see flashes or streaks of light.

✓ Conditions Increasing Risk:

Your chance of experiencing problems increases when taking this drug for more than five years, if older than sixty, or have pre-existing kidney disease.

Heart Health

✓ Rhythm Problems:

The drug can cause QT prolongation, which means it interferes with the heart’s electrical rhythm.

✓ Health Background:

Inform your physician of any previous heart conditions, heart failure, or abnormally slow heartbeat.

✓ Multiple Medications:

Take note if you are on other medications that alter heart rhythms (e.g., antibiotics or antipsychotic drugs).

Hypoglycemia Risk:

HQ Star has the ability to reduce your blood sugar levels. When you have diabetes and are under medications such as insulin or glucose-lowering medication, you should monitor your blood sugar level since there will be changes in your other drug doses.

When Not To Use:

✓ Allergies:

If you have had a reaction to Hydroxychloroquine or other medicines such as Chloroquine, you should be careful.

Hydroxychloroquine can cause problems for people who are allergic to it or to similar medicines.

✓ Retinopathy:

The drug can build up in the retina. Cause: Bulls-eye maculopathy. Therefore, it is usually not recommended for people with existing retina damage or serious vision problems.

Specific Genetic Conditions:

✓ G6PD Deficiency:

Individuals suffering from G6PD deficiency have a high risk of haemolysis, which results in severe anaemia when this drug is consumed.

✓ Porphyria:

Consumption of this drug may result in a serious case of porphyria, which is a blood disorder.

Storage And Disposal:

Store the HQ Star 400mg in an area of low heat and humidity. The temperature should not exceed more than 30 degrees Celsius.

• Store below 30°C
• Keep away from moisture and direct sunlight
• Keep out of reach of children

Where To Buy HQ Star 400 Mg In Australia?

You can use a reliable website like australiarxmeds.com for discreet delivery in Australia. You can order HQ Star 400mg online from pharmacies. Make sure you only buy from verified and licensed sources to ensure authenticity and safety.

Summary

HQ Star 400 is a prescription medicine containing Hydroxychloroquine 400 mg, commonly used to treat autoimmune conditions such as rheumatoid arthritis and lupus, as well as to prevent and treat malaria.

It works by reducing inflammation and regulating immune system activity.