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Learn About The Side Effects Of Sildenafil

By Ezra Allen, Jan-27-2026  

Learn About The Side Effects Of Sildenafil
Written By-Ezra Allen  Medical Reviewer, Senior Writer
 • Published: 01/27/2026
• Updated: 01/27/2026

🏷️ Key Facts:

◾ Sildenafil, the most common generic element you will find in a lot of generic and FDA-approved brand names, is used in the making of ED drugs. Around the world, people also refer to it by the names “Blue Viagra” or “Blue Pill.”

◾ Sildenafil’s action helps these impotent men to be able to get a hard erection and enjoy having sex once again. However, it does come with some risks and side effects you should be aware of.

◾ In this blog post, we are going to give you a complete idea about the side effects of Sildenafil. We will check out when these side effects occur, check out the mild and severe side effects, and also tell you the reason behind them. Don’t worry, we also have some solutions to help you avoid these side effects.

 

Sildenafil – A Basic Idea About This Generic Drug Substance

  • Sildenafil is the first of its kind to be approved by the global drug-approving body, the US FDA, for the treatment of erectile dysfunction.
  • In case you do not have an idea of what ED is, it is a potential disability that cuts down the ability of men to have a strong and consistent erection. Without the ability to get a hard erection, men lose their penetration ability and thus cannot have sex.
  • However, it is with the help of viagra that one potentially recovers from this disability. It brings you close to your normal sex life once again, as you can get a strong erection pretty fast.
  • We will tell you about the effects of Sildenafil later on, but for now, remember that it comes from a class of drugs known as the PDE-5 inhibitors.
  • It is a prescription element. So, regardless of the brand of sildenafil you are buying, you will always need a prescription from a doctor first.

Key Highlights of Sildenafil

Key AspectHighlight
Active IngredientSildenafil Citrate
Brand NameViagra®, Revatio®
Drug CategoryPDE-5 Inhibitor
FormulaC22H30N6O4S
Onset Action30–60 minutes
Prescription Status (Australia)Prescription-only (Schedule 4 – TGA)
Generic AvailableYes (Sildenafil – lower cost)
Sexual Stimulation RequiredYes

Effects Of Sildenafil

Sildenafil, as we told you above, can change the failure of penis erections. It can do so with its action on the PDE-5 hormones initially, which it suppresses completely.

On the suppression of the PDE-5 hormones, the gateway to the cGMP hormones opens, and it increases in the blood.

Soon, it is also able to activate nitric oxide, whose action is quite important in the process of getting you a hard erection. The fixed role of nitric oxide is to cause dilation, because of which the arteries relax and there is an increase in the flow of blood to the penis tissues.

Because of this, you are easily able to get more sensitivity in the penis area because you get a hard erection each time during stimulation.

Sildenafil taking effects

Side Effects Of Sildenafil: When Do They Occur?

There is a possibility that you can end up with side effects from using drugs like Cenforce 100. Depending on the severity and type of side effect, it can occur because of-

Overdose

This is when you take a higher strength of sildenafil than what you are supposed to. Remember that this medicine is only suitable as per your age and health, in a fixed dose.

Interaction With Other Medicines

As per the FDA, there are some other medicines capable of interacting with Sildenafil and causing side effects. Here is a list of such drugs:

  • Anticoagulants
  • Blood thinners
  • Medicines that contain nitrates
  • Alpha and beta blockers

Alternatives That May Also Require Prescriptions

Interaction With Alcohol And Addictive Substances

The FDA states that patients using any brand of Sildenafil must refrain from the use of alcohol and any form of addictive substances like narcotic drugs. These types of substances are also well known for causing a wide range of side effects.

When And How Should You Take Sildenafil?

Side Effects Of Sildenafil

So, with an idea of what causes side effects after using Cenforce 200 and other brands of Sildenafil, it is finally time to take a look at the side effects.

Mild Issues

  • Headache
  • Dizziness
  • Nausea
  • Palpitations
  • Flushing
  • Vomiting
  • Diarrhea
  • Mouth dryness

Why Do These Side Effects Occur?

It can occur because of a mild overdose or your body’s adjustment to the action of the medicine.

How To Get Rid Of These Side Effects?

As per a study of mild side effects of Sildenafil, most will get away on their own within 4 to 5 days. In case it does not, and it still keeps occurring or gets severe with time, you will need to consult with the doctors.

Severe Side Effects

Even though it is rare, Sildenafil is also known to cause a few major side effects in patients. Some of the common issues include:

  • Priapism, where your erections won’t go away even after the drug action is over.
  • Increase in heartbeat.
  • Rapid changes in BP, sometimes going up and then falling.
  • Increased rate of breathing
  • Blurred vision

What To Do With Such Side Effects?

The FDA states that if such side effects occur, which is rare at about a 1 to 2% chance only, you should immediately stop taking the medicines. Get in touch with your doctor.

When To Talk To A Doctor

Consult a healthcare professional if side effects are persistent, worsen, or interfere with daily life. Medical advice is especially important if you have underlying health conditions.

How To Avoid Having Side Effects With Sildenafil?

To avoid getting into trouble after use of Sildenafil brands like Cenforce 150, here are a few simple steps that you can take:

  • Avoid the use of alcohol, narcotic drugs.
  • Avoid taking a higher dose.
  • Avoid taking the next medicine for 24 hours are over.
  • Take it at the same time daily.
  • Start with a smaller dose.

Final Thoughts

So, as you can see in this article, we have given you a complete idea about the range of side effects that occur when using Sildenafil. We have also told you what to do if such side effects arise and given some tips to avoid these issues completely.

FAQs

What to do if mild side effects intensify within a few days?
In this case, you need to consult with a doctor and find a suitable medicine that addresses these side effects.
Is it possible to have a heart attack after taking Sildenafil?
Such cases are rare, but it is possible with a severe drug interaction or taking a heavy overdose.
Can patients with diabetes disorder use Sildenafil?
Ask your doctor; however, remember that it is not safe to use Sildenafil if you have type II diabetes.
Ezra Allen (Medical Reviewer, Senior Writer)

Years of Experience: 12+ Years Education: Master of Sexology - [University of Sydney] MBBS (Bachelor of Medicine, Bachelor of Surgery) - [Torrens University Australia] BSc in Medical Laboratory Technology -…

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