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Ismo 20 Mg

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Active-Ingredient Isosorbide Mononitrate
Manufacturers
Packaging 30 tablets in 1 strip
Strength 20mg
Delivery-Time 6 To 15 days
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Active-Ingredient Isosorbide Mononitrate
Manufacturers
Packaging 30 tablets in 1 strip
Strength 20mg
Delivery-Time 6 To 15 days

Description

Last Updated on ✔ Medically Reviewed by Dr. Arjun Srivastav

Ismo 20 mg is a prescription medicine that belongs to the nitrate class. It is used for the prevention and management of angina.

Each tablet contains isosorbide mononitrate 20 mg as its active ingredient. The 20 mg strength refers to the amount of this compound in every single tablet.

Doctors prescribe it to help reduce the frequency of angina episodes in people whose chest discomfort follows a recognised pattern linked to coronary artery disease. The dosage and timing should always follow the instructions of a healthcare professional rather than a fixed general schedule.

This page brings together the product information, common questions and safety points in one place. You can understand what Ismo 20 mg tablet is and how it is meant to be used.

What Is Ismo 20 Mg?

Ismo 20 mg is a tablet preparation where the active ingredient is isosorbide mononitrate at a strength of 20 mg per tablet. It sits within a group of medicines called nitrates, which are used in the management of certain heart conditions.

The 20 mg figure describes the quantity of the active compound present in each unit. The total amount a person takes over a day is decided by the prescriber based on individual need.

Nitrates as a class are known for their effect on blood vessels. Isosorbide mononitrate is the mononitrate form, which the body processes in a way that supports a sustained effect over several hours. This is one reason it is chosen for prevention rather than for situations where a very rapid response is required.

In plain terms, the medicine works by easing the workload the heart has to handle. When the demand on the heart is reduced, the conditions that typically bring on angina symptoms become less likely to occur during ordinary activity.

It is intended for angina management and prevention as part of a prescribed plan. It is not meant for treating every kind of chest discomfort on your own. Any new, changing or unexplained chest pain still needs proper medical assessment before it is assumed to be angina.

Information Details
Brand Ismo 20 mg
Active ingredient Isosorbide mononitrate
Strength 20 mg
Medicine class Nitrate
Main use Angina prevention and management
Dosage form Tablet

What Is Ismo 20 Mg Used For?

The main use of Ismo 20 mg is in the prevention and management of angina. Angina is the chest discomfort that can arise when the heart does not receive enough oxygen for the effort being demanded of it.

By reducing the workload on the heart, the medicine aims to lower the chance that ordinary daily activities will trigger those symptoms. It is taken on a planned schedule to keep symptoms from appearing as often.

It helps to draw a clear line between prevention and the treatment of an acute attack. Ismo 20 mg is not designed to act fast enough to stop an episode that has already begun.

People who experience sudden angina are usually advised to use a separate fast acting medicine, such as glyceryl trinitrate spray or tablets, for immediate relief. Their doctor explains how the two fit together.

It is equally important not to assume that Ismo 20 mg suits every type of chest pain. Discomfort in the chest can come from many causes, and some of them need urgent attention rather than a long term prescription.

The underlying reason for any chest pain should be assessed by a healthcare professional. The right approach is then chosen for the actual cause.

Is Ismo 20 Mg Used for Sudden Chest Pain?

Ismo 20 mg is used as prescribed for the prevention and management of angina. It is not meant to be treated as a medicine for self treating sudden or unexplained chest pain.

It does not act quickly enough to relieve an episode that has already started. Relying on it during an acute event would not be appropriate.

Acute or severe chest pain requires urgent medical assessment. Any new chest discomfort that appears for the first time or feels different from the usual pattern should be checked without delay.

How Does Ismo 20 Mg Work?

Inside the body, isosorbide mononitrate acts as a donor of nitric oxide. That nitric oxide sets off a process that relaxes the smooth muscle within the walls of blood vessels. The result is a widening of those vessels.

The effect is most noticeable on the veins, the vessels that carry blood back toward the heart. When the veins widen, less blood returns to the heart at any given moment. This reduces the pressure inside the heart before each beat.

With the preload lowered, the heart pumps against a smaller load and demands less oxygen to do its work. The oxygen requirement of the heart drops while the effort of daily life stays the same.

That is the core reason the medicine is used for prevention on a regular schedule rather than for immediate relief during an attack. The situations that usually provoke angina become less likely to do so.

💡 Tip

Ismo 20 mg works as prescribed to help prevent and manage angina. Take it according to your healthcare professional’s instructions rather than changing the dose or timing yourself.

Ismo 20 Mg Dosage and How to Take It

The dose of Ismo 20 mg is determined according to the condition of the individual and the advice of the prescriber. The fact that the tablet is a 20 mg strength does not mean everyone follows the same schedule.

The total daily amount and the spacing between doses are tailored to each person. According to the product information, the usual regimen for the 20 mg tablet is one tablet taken twice daily, with the two doses spaced about seven hours apart.

For many people this means taking the first dose soon after waking and the second dose seven hours later. The daily amount can range from 20 mg up to 120 mg in divided doses. The prescriber decides where within that range a person should sit.

When someone is new to nitrate treatment, the doctor may begin with a lower strength for the first few days before moving to the 20 mg tablet. This gradual start helps the body adjust.

The tablet should be swallowed whole with a drink of water and not chewed or crushed. It is taken at the times the healthcare professional has set, and those times should be kept consistent each day.

The spacing is deliberate. It creates a nitrate free interval that helps maintain the effect of the medicine over time.

You should not independently increase, decrease or repeat a dose. If the medicine causes troublesome dizziness or headaches, the right step is to contact the healthcare professional rather than adjusting the schedule yourself.

Stopping the medicine suddenly is also not advised. Treatment with nitrates is generally reduced gradually under medical guidance.

What If You Miss an Ismo 20 Mg Dose?

A missed dose should be handled according to the instructions from the healthcare professional or pharmacist. If you remember and the next scheduled dose is still some time away, take it as soon as you notice.

If it is already close to the next dose, skip the one you missed and continue with the usual routine. Do not take an extra tablet to make up for the one that was missed, because doubling up can lower blood pressure more than intended.

🔔 Reminder

If you miss a dose of Ismo 20 mg, follow the missed-dose instructions provided by your healthcare professional or product information. Do not take extra tablets to make up for a missed dose.

What Happens If You Take Too Much Ismo 20 Mg?

Taking too much Ismo 20 mg can cause an excessive fall in blood pressure. The symptoms that may follow include severe dizziness, weakness, fainting, headache and a rapid heartbeat.

If an overdose is suspected, urgent medical advice should be sought straight away rather than waiting to see whether the symptoms settle on their own. The exact maximum dose is something the prescriber sets for the individual, so a fixed general figure is not given here.

Ismo 20 Mg Side Effects

Side effects vary from person to person, and not everyone who takes Ismo 20 mg will experience them. Many of the effects that do appear tend to be most noticeable in the early days of treatment and often become less troublesome as the body adjusts.

Knowing what is common and what needs prompt attention helps you respond appropriately rather than stopping the medicine on your own.

Common Side Effects
Serious Side Effects
Common Side Effects
😵 Dizziness
📉 Low blood pressure
😳 Flushing
🤮 Nausea
💓 Increased heart rate or palpitations
Serious Side Effects
🚨 Fainting or severe dizziness
💔 Very low blood pressure
🫀 Severe or worsening chest pain
🚑 Severe allergic reaction
🫁 Difficulty breathing
😵 Dizziness
🚨 Fainting or severe dizziness
📉 Low blood pressure
💔 Very low blood pressure
😳 Flushing
🫀 Severe or worsening chest pain
🤮 Nausea
🚑 Severe allergic reaction
💓 Increased heart rate or palpitations
🫁 Difficulty breathing

These effects are not common, but they warrant immediate medical attention if they occur. The response to any serious symptom should be to seek help promptly rather than to wait and observe.

Ismo 20 Mg Precautions and Warnings

Several precautions apply to Ismo 20 mg, and most of them centre on blood pressure. The medicine lowers the workload on the heart partly by widening blood vessels, so it can also reduce blood pressure. That effect matters more for some people than others.

Anyone who already has low blood pressure or who becomes dizzy when standing up quickly should discuss this with the prescriber before starting treatment. Existing cardiovascular conditions need to be part of the conversation with the doctor, because the overall heart picture influences whether this medicine is appropriate and at what dose. People taking medicines for cardiovascular conditions should make sure their healthcare professional knows about all medicines they use, including those listed under heart care medicines.

The risk of dizziness or fainting can be higher in older adults and in people who are more sensitive to changes in blood pressure. Standing up slowly and taking care with balance is sensible during the early period of use.

Alcohol can worsen the dizziness and the blood pressure lowering effect, so the prescriber’s advice on drinking should be followed. It is also important to inform the healthcare professional about every other medicine being taken, including those bought without a prescription, because several combinations need attention.

Treatment should not be stopped or changed without medical advice. The distinction between prescribed nitrate therapy and self treatment of unexplained chest pain should always be kept in mind.

⚠️ Warning

Ismo 20 mg can lower blood pressure and may cause dizziness or fainting. Use caution when standing up, and avoid driving or operating machinery if you feel dizzy or light-headed.

Ismo 20 Mg Drug Interactions

Ismo 20 mg can interact with several other medicines and substances. These interactions are worth understanding because they can change how the medicine behaves or raise the risk of side effects.

The main groups to be aware of include:

  • Medicines that lower blood pressure, which can add to the effect of Ismo 20 mg and push blood pressure lower than intended
  • Other nitrate medicines, since the combined effect on the blood vessels is greater than either medicine alone
  • Any medicine known to increase the risk of low blood pressure, which should be reviewed with the prescriber before use
  • Alcohol, which can intensify the blood pressure lowering and the dizziness that some people feel

The combination of alcohol and nitrates is something the healthcare professional takes into account when giving advice about drinking during treatment.

A particularly important interaction involves a group of medicines called PDE5 inhibitors. These are discussed in detail below because of the safety concern they raise when used with nitrates.

Ismo 20 Mg and ED Medicines

ED medicines that belong to the PDE5 inhibitor group include sildenafil, tadalafil and vardenafil. These medicines also widen blood vessels.

When they are combined with a nitrate such as Ismo 20 mg, the effect on blood pressure can become large and potentially dangerous. For this reason, nitrates and PDE5 inhibitors should not be combined unless a healthcare professional specifically confirms that it is safe in the individual situation.

This is a medical safety point first and foremost, and it applies regardless of the reason the ED medicine is being used.

🚨 Important

Do not take Ismo 20 mg with PDE5 inhibitors such as sildenafil, tadalafil or vardenafil unless a healthcare professional specifically confirms that the combination is safe. Combining nitrates with these medicines can cause a dangerous drop in blood pressure.

Ismo 20 Mg and Alcohol

Alcohol can worsen the dizziness and the lowering of blood pressure that Ismo 20 mg may cause. When the two are combined, the likelihood of feeling faint or unsteady can increase.

The effect may be more pronounced after the first dose or after a dose increase. The right approach is to follow the advice of the healthcare professional regarding alcohol.

The level of caution needed can depend on the individual and on any other medicines being taken. Rather than applying a blanket rule about drinking, the guidance from the prescriber reflects the specific situation of the person using the medicine.

Can You Develop Tolerance to Ismo 20 Mg?

Nitrate tolerance can occur when the body is exposed to a continuous level of the medicine without a break. When tolerance develops, the medicine can become less effective over time.

This is the opposite of what long term prevention aims to achieve, and it is the reason the prescribed dosing schedule matters. The spacing of doses is designed to create a nitrate free interval within each day, which helps maintain the effect of the treatment.

For the same reason, you should not change the timing or frequency yourself. You should not take additional tablets simply because the medicine feels as though it is becoming less effective. If that impression arises, the prescriber is the right person to review the schedule.

Ismo 20 Mg Storage and Handling

Ismo 20 mg should be stored according to the instructions on the product packaging and the guidance from the pharmacy. The tablets should be kept away from excessive heat and moisture, and they should remain out of the reach of children.

Any tablets that are damaged or that have been stored improperly should not be used.

Where to Buy Ismo 20 Mg

Ismo 20 mg is a prescription medicine, so it should be obtained through a registered pharmacy with a valid prescription. If you are looking to order Ismo 20 mg tablet online, AustraliaRXMeds is a source where this medicine can be purchased.

Always check that the pharmacy asks for a prescription and provides clear product information before you buy. The dosage and timing should still follow the instructions of your healthcare professional, whether the medicine is bought from a local pharmacy or ordered online.

FAQs

What is Ismo 20 mg used for?

Ismo 20 mg is primarily prescribed for the prevention and management of angina. It is taken on a regular schedule to reduce the frequency of angina episodes rather than to relieve an attack that has already begun.

What is the active ingredient in Ismo 20 mg?

The active ingredient in Ismo 20 mg is isosorbide mononitrate, and each tablet contains 20 mg of this compound.

What are the common side effects of Ismo 20 mg?

Common side effects include headache, dizziness, low blood pressure, flushing, nausea and an increased heart rate. Headache is a recognised effect of nitrate medicines and often becomes less troublesome with continued use.

Can Ismo 20 mg be taken with sildenafil?

Ismo 20 mg should not be combined with sildenafil or other PDE5 inhibitors unless a healthcare professional specifically confirms it is safe, because the combination can cause a dangerous fall in blood pressure.

Can Ismo 20 mg cause low blood pressure?

Yes, Ismo 20 mg can lower blood pressure, and this may cause dizziness or fainting, particularly at the start of treatment or after a dose increase. Anyone who already has low blood pressure should discuss this with the prescriber.

Can I drink alcohol while taking Ismo 20 mg?

Alcohol can increase the dizziness and the blood pressure lowering effect of Ismo 20 mg. The guidance of the healthcare professional on drinking should be followed, since the right level of caution depends on the individual situation.

Is Ismo 20 mg used for sudden chest pain?

Ismo 20 mg is used for prevention and management on a planned schedule and is not meant for sudden chest pain. Any new, severe or changing chest discomfort requires urgent medical assessment rather than self treatment.

About the Doctor

Dr. Arjun Srivastav

Medical Reviewer (Pharm D)

✔ Medically Reviewed • Updated: 10/06/2026

Education: Graduate Diploma in Clinical Practice - University of Sydney,

Clinical Pharmacist (Pharm D) Doctor of Medicine (MD) – University of Melbourne Biomedical Engineering – Monash University Graduate Diploma in Clinical Practice - University of Sydney, Arjun Srivastav is a dedicated Clinical Pharmacologist and the E-commerce Operations Manager at AustraliaRxMeds. With a Doctor of Pharmacy (Pharm D) and over 10 years of clinical experience at prestigious institutions like Wockhardt and Apollo Hospitals, Arjun specializes in drug safety, digital healthcare accessibility,...

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