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Betnovate S

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Active-Ingredient Betamethasone
Manufacturers
Packaging 30g Tubes
Strength 20g
Delivery-Time 6 To 15 days
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Active-Ingredient Betamethasone
Manufacturers
Packaging 30g Tubes
Strength 20g
Delivery-Time 6 To 15 days
Last Updated on ✔ Medically Reviewed by Dr. Arjun Srivastav

What Is Betnovate S Ointment?

Betnovate S is a topical ointment containing two active ingredients, betamethasone valerate and salicylic acid. It is a combination of a corticosteroid and a keratolytic ingredient. The formulation is described in the manufacturer’s prescribing information for selected dry, scaly and thickened skin conditions.

Unlike standard Betnovate, which contains betamethasone valerate as its active ingredient, Betnovate S also contains salicylic acid. This difference is important when checking the product composition and its prescribing instructions.

Betnovate S is intended for external skin application. Its use, application frequency and treatment period should follow the instructions provided by the prescribing healthcare professional. Betnovate-S is a topical preparation used for certain inflammatory and scaling skin conditions. Other treatment options are available in our range of skin care medicines.

Betnovate S Ingredients and Composition

The formulation contains two active ingredients in a greasy ointment base. Each has a different pharmacological classification.

Product specification Information
Product name Betnovate-S
Active ingredient 1 Betamethasone valerate
Equivalent strength Betamethasone 0.1% w/w
Active ingredient 2 Salicylic acid
Strength 3% w/w
Dosage form Ointment
Route of administration Topical
Base ingredients Liquid paraffin and white soft paraffin
Manufacturer GlaxoSmithKline Pharmaceuticals Limited

The manufacturer’s product information identifies the concentrations as betamethasone valerate equivalent to betamethasone 0.1% w/w and salicylic acid 3% w/w. Pack size should be confirmed against the supplied tube and carton.

Betamethasone Valerate 0.1%

Betamethasone valerate belongs to the corticosteroid group of medicines. In topical preparations, this ingredient is associated with anti inflammatory activity. Its pharmacological action involves several processes that regulate inflammatory responses in the skin.

The prescribing information describes its role in reducing inflammatory activity and associated skin reactions. The concentration listed for Betnovate-S is equivalent to betamethasone 0.1% w/w.

Salicylic Acid 3%

Salicylic acid is classified as a keratolytic ingredient. It is included in topical preparations containing this ingredient for its action on accumulated keratin and scaling.

In the Betnovate-S formulation, salicylic acid is present at 3% w/w. The product information describes its role in conditions involving excessive scaling and thickened skin. It also notes that salicylic acid can influence the absorption of the corticosteroid component.

What Is Betnovate S Used For?

The manufacturer’s prescribing information lists Betnovate S for selected subacute and chronic dry or hyperkeratotic skin conditions that are suitable for topical corticosteroid therapy.

The listed conditions include the following.

Psoriasis and Thickened Skin

Psoriasis is a skin condition associated with changes in skin cell turnover and the formation of dry, scaly patches. Some forms involve areas of thickened skin.

The Betnovate S prescribing information includes psoriasis among its listed indications, with an important exclusion for widespread plaque psoriasis. Use in psoriasis requires careful medical supervision because topical corticosteroid treatment has specific precautions in this condition.

Chronic Eczema and Dermatitis

The product information includes chronic eczema, allergic skin diseases and endogenous eczema, also known as atopic dermatitis.

These conditions can involve different patterns of skin inflammation, dryness and irritation. Their diagnosis and suitability for a particular topical preparation need to be assessed individually.

Other Hyperkeratotic Skin Conditions

The manufacturer’s document also lists several other conditions:

• Keratosis palmaris et plantaris, involving keratinisation of the palms and soles.

• Seborrhoeic eczema.

• Dyshidrosis lamellosa sicca, involving dry and scaly changes on the palms, sides of the fingers or soles.

• Lichen planus.

• Lichen simplex.

• Ichthyosis.

These are product information listed indications, not a recommendation to use the ointment for every skin condition with similar symptoms. A healthcare professional should establish the diagnosis before treatment.

How Does Betnovate S Work?

Betnovate S contains ingredients from two different pharmacological groups. The manufacturer’s information describes their respective actions separately.

Anti Inflammatory Action

Betamethasone valerate is a topical corticosteroid. Corticosteroids act through several mechanisms involved in inflammatory responses. These processes include effects on inflammatory cells and chemical mediators.

Keratolytic Action

Salicylic acid has keratolytic properties. Its action relates to the breakdown and removal of accumulated keratin in scaling skin conditions.

Why Are Both Ingredients Combined?

The formulation brings together a corticosteroid and a keratolytic ingredient. The product information describes salicylic acid as helping facilitate corticosteroid penetration in hyperkeratotic and scaling conditions.

This combination distinguishes Betnovate-S from standard Betnovate ointment, which does not contain salicylic acid.

How to Apply Betnovate S Ointment

Betnovate S is intended for external application only. Follow the directions supplied with the product and those given by the prescribing healthcare professional.

The general application instructions in the manufacturer’s prescribing information are:

  1. Clean the affected skin area gently and allow it to dry.
  2. Apply a thin layer of ointment over the prescribed area.
  3. Spread the preparation evenly without applying unnecessary pressure.
  4. Allow sufficient time for the ointment to be absorbed before applying an emollient.
  5. Wash your hands after application unless the hands are the area being treated.

Avoid getting the preparation into the eyes. Do not use airtight coverings or dressings unless specifically directed by a healthcare professional.

The quantity and application area should remain within the prescribed instructions. Applying more ointment or extending its use without advice can increase exposure to its active ingredients.

💡 Tip

Apply a thin layer of Betnovate-S Ointment to the affected skin as directed. Allow it to absorb before applying an emollient.

Betnovate S Dosage and Treatment Duration

The manufacturer’s prescribing information describes a thin application to the affected area twice daily, in the morning and evening, unless a different schedule has been prescribed. For some skin disorders, once daily application may be sufficient.

The amount required depends on the prescribed treatment area. Use the minimum quantity and follow the recommended treatment period rather than adjusting the frequency independently.

The product information states that reassessment is necessary if no improvement is observed within four weeks. This does not mean treatment should automatically continue for four weeks. The prescribing healthcare professional should determine the appropriate duration.

Children require particular care because topical corticosteroid absorption and adverse effects can differ from those in adults. Betnovate-S is contraindicated in children under one year according to the cited manufacturer’s information.

Other Dosage:

🔵 Reminder

Use Betnovate S only for the prescribed duration. If your skin condition does not improve within four weeks, seek medical advice for reassessment.

Possible Side Effects of Betnovate S

As with other topical preparations containing corticosteroids and salicylic acid, unwanted reactions may occur during use. The type and frequency can vary according to individual circumstances and application conditions.

😊 Common Side Effects

🚨 Serious (Rare) Side Effects

😊 Common Side Effects

🔥 Burning sensation at the application site
🖐️ Itching
😣 Skin irritation
🌵 Dryness or peeling
🔴 Local skin discomfort

🚨 Serious (Rare) Side Effects

🦠 Secondary skin infections
🩹 Skin thinning or atrophy
🩸 Stretch marks
🔍 Visible small blood vessels
⚠️ Allergic contact dermatitis
🔥 Burning sensation at the application site
🦠 Secondary skin infections
🖐️ Itching
🩹 Skin thinning or atrophy
😣 Skin irritation
🩸 Stretch marks
🌵 Dryness or peeling
🔍 Visible small blood vessels
🔴 Local skin discomfort
⚠️ Allergic contact dermatitis

Prolonged use, extensive application and increased absorption can be associated with systemic corticosteroid effects. The product information also records blurred vision and other visual disturbances as matters requiring assessment.

Contact a healthcare professional if an unexpected reaction occurs. Seek prompt medical assessment for visual changes or symptoms suggesting a significant adverse reaction.

Warnings and Precautions When Using Betnovate S

Read the product information and follow professional instructions before using Betnovate S. Several factors are particularly important when applying a preparation containing betamethasone and salicylic acid.

• Large treatment areas: Extensive application can increase the amount of active ingredients absorbed through the skin.

• Prolonged use: Continuous application over an extended period can increase the risk of corticosteroid related adverse effects.

• Occlusive dressings: Airtight coverings can increase absorption and create conditions associated with skin infection.

• Facial application: The face is more susceptible to skin thinning from prolonged corticosteroid exposure.

• Broken skin: Damaged skin barriers can influence the absorption of topical ingredients.

• Pregnancy and breastfeeding: Obtain professional advice before use. The manufacturer’s information recommends considering the potential risks and benefits. During breastfeeding, the ointment should not be applied to the breasts.

• Flammability: The preparation contains paraffin. Clothing, bedding and dressings that come into contact with it may present a fire hazard. Keep treated materials away from smoking and naked flames.

These precautions should be considered alongside the directions supplied with the particular product.

⚠️ Warning

Avoid applying Betnovate-S to untreated bacterial, fungal or viral skin infections. Prolonged use, large application areas and covering treated skin can increase the risk of side effects.

Who Should Avoid Betnovate S?

The manufacturer’s prescribing information lists several conditions in which Betnovate S should not be used. Skin conditions caused by bacteria, fungi or viruses require appropriate assessment and treatment. Different options are listed in our medicines for skin infections category.

These include:

• Known hypersensitivity to any ingredient in the preparation.

• Acne vulgaris.

• Rosacea.

• Perioral dermatitis.

• Itching without inflammation.

• Perianal and genital itching.

• Primary infected skin lesions caused by fungal, viral or bacterial infections.

• Ulcerated skin lesions.

• Skin conditions in children under one year of age.

This list relates to the cited Betnovate-S product information. A healthcare professional should review the individual’s skin condition and medical history before prescribing the preparation.

❗ Important

Betnovate-S contains a topical corticosteroid and salicylic acid. Avoid contact with the eyes and do not use it on the face or sensitive areas unless specifically advised by a healthcare professional.

Drug Interactions and Other Skin Treatments

The manufacturer’s information identifies a potential interaction with medicines that inhibit the CYP3A4 enzyme. Examples include ritonavir and itraconazole. These medicines can affect corticosteroid metabolism and may increase systemic exposure.

Tell your healthcare professional about prescription medicines, other topical corticosteroids and medicated skin preparations being used at the same time. Do not combine topical treatments on the same area without appropriate instructions.

How to Store Betnovate S Ointment

Store the ointment protected from light at a temperature not exceeding 25°C, according to the cited manufacturer’s information. Do not freeze the product. Keep the tube closed and out of reach of children. Check the expiry date printed on the packaging before use.

AustraliaRxMeds provides product information to help customers understand the composition, intended uses and precautions associated with Betnovate-S Ointment. We encourage responsible use and recommend consulting a qualified healthcare professional to confirm whether this topical treatment is suitable for your skin condition.

Medical Disclaimer

This page provides general product information based on the cited manufacturer’s prescribing document. It does not replace a medical diagnosis, prescription instructions or individual advice from a qualified healthcare professional.

FAQs

What is Betnovate S ointment used for?

The manufacturer’s product information lists selected dry, scaly and hyperkeratotic skin conditions, including certain forms of psoriasis, eczema, dermatitis and other skin disorders.

Does Betnovate-S contain salicylic acid?

Yes. The cited formulation contains salicylic acid 3% w/w alongside betamethasone valerate equivalent to betamethasone 0.1% w/w.

What is the difference between Betnovate and Betnovate-S?

Standard Betnovate contains betamethasone valerate. Betnovate-S contains betamethasone valerate and an additional ingredient, salicylic acid. Their compositions and product instructions should not be treated as interchangeable.

Can Betnovate-S be used for psoriasis?

Psoriasis is included in the manufacturer’s listed indications, except widespread plaque psoriasis. Use requires appropriate medical supervision.

Can Betnovate-S be used for acne?

No. Acne vulgaris is listed as a contraindication in the manufacturer’s Betnovate-S prescribing information.

How often should Betnovate-S be applied?

The manufacturer’s usual instruction is a thin application twice daily unless prescribed otherwise. Once daily may be sufficient for some skin disorders. Follow the directions provided for your treatment.

Can Betnovate-S be used on the face?

Facial application requires particular caution because prolonged corticosteroid exposure can cause skin thinning. Do not apply it to the face unless a healthcare professional has specifically advised you to do so.

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  1. Review Avatar image

    Aahan Z. Batu –

    I have the greatest problem with acne. My face has been plagued with acne for five years, and no medication seems to help. The dermatologist gave me the green light to use Betnovate S, which was recommended to me by a friend. Fortunately, it appears to be working for me. Acne on my skin has drastically decreased in number, and the extra oil that used to trigger it has disappeared.
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About the Doctor

Dr. Arjun Srivastav

Medical Reviewer (Pharm D)

✔ Medically Reviewed • Updated: 11/12/2026

Education: Graduate Diploma in Clinical Practice - University of Sydney,

Clinical Pharmacist (Pharm D) Doctor of Medicine (MD) – University of Melbourne Biomedical Engineering – Monash University Graduate Diploma in Clinical Practice - University of Sydney, Arjun Srivastav is a dedicated Clinical Pharmacologist and the E-commerce Operations Manager at AustraliaRxMeds. With a Doctor of Pharmacy (Pharm D) and over 10 years of clinical experience at prestigious institutions like Wockhardt and Apollo Hospitals, Arjun specializes in drug safety, digital healthcare accessibility,...

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